DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ms(3)76Cc and CG32436

DIOPT Version :9

Sequence 1:	NP_649136.1	Gene:	ms(3)76Cc / 40142	FlyBaseID:	FBgn0036895	Length:	1174	Species:	Drosophila melanogaster
Sequence 2:	NP_730622.1	Gene:	CG32436 / 40362	FlyBaseID:	FBgn0052436	Length:	1737	Species:	Drosophila melanogaster

Alignment Length:	643	Identity:	141/643 - (21%)
Similarity:	263/643 - (40%)	Gaps:	121/643 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 PKQQEANVLNF-------ATYLKAFALIYVLPETDWTAEKIDMLLEEGTDLFRASSDVNQGHDDP 152
            || :|.|.|.:       ...:.||...:.|....||...:|.:|:.|..|.:.|:|:|. ..|.
  Fly   301 PK-KEPNRLQYYYRPSEIGAIIVAFVETFRLNPDFWTGSTMDGILKRGVKLTKKSADLNY-KSDV 363

  Fly   153 DEHKLLEPEIYTNEEKRIKRNFNLEGHTFTLALEPRYLGVGSKPLDQQPPHIIKNLGTILQSFFK 217
            ::..:::.....:....||.:|                   |..|..:|     |:...|..||.
  Fly   364 NDFDIIQQVAERDAAVEIKIHF-------------------SGLLKNEP-----NMYKALSLFFS 404

  Fly   218 SSRYCLLLTRVGHLLIWRR-RRVFFVLDVKGRAKDDLATVKDNGVAMLVCLKSIDNVVHLASNLS 281
            ....|:..:|...||||:| ...:::.|..|| .::.....:.|...|:..:..:::|||.:..|
  Fly   405 KYNACIFTSRDLFLLIWKRCLNSYYIFDPNGR-DENCERNFEEGKCSLMATRYTEHLVHLITKFS 468

  Fly   282 GISPRDEFSIRELVVV---RLETPDGRIYMRDTSHRSIEFKVVNKSYAY---LKGTLHLSLNKDD 340
            .:.|:|||:|.|:.:.   :|:.|.......:..|:.  :..||:::|.   ..|.:|..::.::
  Fly   469 DLQPQDEFNIFEISLTQYGKLKEPPINSAENEEYHKL--WAPVNENFAVKTAATGGIHQPISGNE 531

  Fly   341 PVRNRSSLMVAVGSVLASKIDHPANWDTNMLDRLISYGVELCRSC----------WSDCLRDRRP 395
               ..:||:|::.:::.|:.:....|....:|.:|.|||...::.          |    ::::|
  Fly   532 ---KNASLVVSLIALIYSEFELAKLWKPGTVDDIIRYGVAYYKTLRKKFRLDGKRW----KNKKP 589

  Fly   396 ----IDLDTFPTQLRMGQFVLELKLIPNVRTGHWRCGVRIIGTDFEAHVSQALKELGNV------ 450
                :||   |....||.|...::..|.:..||    |.......|:.::.||.:|.|:
  Fly   590 HLNVVDL---PEMFLMGAFKATVRKHPFMINGH----VADCRNYLESQLTMALHQLFNLPQWPSA 647

  Fly   451 VFQINNQMYAIWLKDGFYYLVDPYRHTIVGTHVAEDKAEGAKWATVRMFRDQLTMLSVFHQLLKE 515
            :.||:|.:.|:|....|:|:.||:|....|..|..|.......|.:::.....:.:.|.:....:
  Fly   648 LLQIDNSVMAVWRDREFFYVFDPFRRNRTGLVVDPDDYSIKGLAVLQLHATFDSFVRVIYMNALK 712

  Fly   516 SNRQSAYYVHVVR---IRNL-AECPE-----GYAL--------LPMPDGKDSCEVKSLNETIFF- 562
            ..|...:::|.||   ||.| ...|:     |..:        .|||:.|....::|:.|...|
  Fly   713 MRRGGKFFIHGVRTGCIRPLQVMTPQTNRFPGLQMGLPTFTDEPPMPELKQKKSIESIPEEDRFP 777

  Fly   563 --NEQQCVR-----VCNKSLAEISD--------YEEDVVSLLTDKSDIDHFQVLDEQQNGGAECE 612
              :|::.|.     :.|..:.|:.:        |:.....||  :||.::.:.|..:...|.|..
  Fly   778 TVDEKEMVEELINMIINSIIKELPEPQPKRPHLYKPAQKVLL--RSDQENLKALRLRIKRGYELG 840

  Fly   613 FCEEEFRTEPLKRRPKGKNTNSKSRVGLSKREQDIKDTSGKMLPTASRTPNDKDSPRL 670
            ..||    |.|||     ....:..|.|....:.:.|.|..::.|......|::..:|
  Fly   841 QEEE----EDLKR-----VLTVEEEVALKSNFKALPDGSWIIVGTTQLPQLDEEMAKL 889

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ms(3)76Cc	NP_649136.1	AF-4	<631..>1049	CDD:282905	7/40 (18%)
CG32436	NP_730622.1	Bud13	1072..>1134	CDD:286779
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28NDP
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0010003
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR40552
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910