Protein Alignment asf1 and ASF1A

DIOPT Version :9

• Sequence 1: NP_001189131.1
• Gene: asf1 / 40141
• FlyBaseID: FBgn0029094
• Length: 218
• Species: Drosophila melanogaster
• Sequence 2: NP_054753.1
• Gene: ASF1A / 25842
• HGNCID: 20995
• Length: 204
• Species: Homo sapiens
• Alignment Length: 209
• Identity: 129/209 - (61%)
• Similarity: 157/209 - (75%)
• Gaps: 17/209 - (8%)

  Fly     1 MAKVHITNVVVLDNPSSFFNPFQFELTFECIEELKEDLEWKMIYVGSAESEEHDQVLDTIYVGPV 65
            ||||.:.|||||||||.|:||||||:||||||:|.||||||:||||||||||:|||||::.||||
Human     1 MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPV 65

  Fly    66 PEGRHIFVFQADPPDVSKIPEPDAVGVTIVLLTCSYRGQEFVRVGYYVNNDYADPEMRENPPTKP 130
            |.|||:||||||.|:...||:.||||||:||:||:||||||:||||||||:|.:.|:|||||.||
Human    66 PAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKP 130

  Fly   131 LFEKLTRNILASKPRVTRFKINWDYGHINGNGNGVENGH------QDEMATDG-PSTSEAASAVI 188
            .|.||.||||||.||||||.|||:     .|...:|:..      |..::||. ||.|:..|.
Human   131 DFSKLQRNILASNPRVTRFHINWE-----DNTEKLEDAESSNPNLQSLLSTDALPSASKGWST-- 188

  Fly   189 HPEDDNSLAMPMEN 202
               .:|||.:.:|:
Human   189 ---SENSLNVMLES 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
asf1	NP_001189131.1	ASF1_hist_chap	1..154	CDD:282572	115/152 (76%)
ASF1A	NP_054753.1	Interaction with histone H3, CHAF1B, and HIRA	1..156		116/159 (73%)
		ASF1_hist_chap	1..154	CDD:398417	115/152 (76%)
		Required for interaction with HIRA	31..37		3/5 (60%)
		Required for interaction with HIRA	155..204		13/50 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145836
Domainoid	1	1.000	254	1.000	Domainoid score	I2066
eggNOG	1	0.900	-	-		E1_COG5137
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8528
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3178
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54218
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001913
OrthoInspector	1	1.000	-	-		otm42018
orthoMCL	1	0.900	-	-		OOG6_101293
Panther	1	1.100	-	-	LDO	PTHR12040
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R94
SonicParanoid	1	1.000	-	-		X1264
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.790