DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment asf1 and unc-85

DIOPT Version :9

Sequence 1:	NP_001189131.1	Gene:	asf1 / 40141	FlyBaseID:	FBgn0029094	Length:	218	Species:	Drosophila melanogaster
Sequence 2:	NP_494837.2	Gene:	unc-85 / 173809	WormBaseID:	WBGene00006817	Length:	275	Species:	Caenorhabditis elegans

Alignment Length:	201	Identity:	89/201 - (44%)
Similarity:	123/201 - (61%)	Gaps:	21/201 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AKVHITNVVVLDNPSSFFNPFQFELTFECIEELKEDLEWKMIYVGSAESEEHDQVLDTIYVGPVP 66
            ::|:|..|.:||||:.|.:.|:.|:|||..|.|..||||:::||||..|.:.|||||:..|||:|
Worm     3 SRVNIVQVQILDNPAMFVDKFKLEITFEVFEHLPHDLEWELVYVGSGTSRDFDQVLDSALVGPIP 67

  Fly    67 EGRHIFVFQADPPDVSKIPEPDAVGVTIVLLTCSYRGQEFVRVGYYVNNDYADPEMRENPPTKPL 131
            ||||.|||.||.||:||||..|.|||:::||.|.|..|||:.:|::|.|:|.:.|::||||::||
Worm    68 EGRHKFVFDADHPDISKIPVDDIVGVSVLLLRCKYNDQEFINMGWFVANEYTEEELKENPPSQPL 132

  Fly   132 FEKLTRNILASKPRVTRFKINWDYGHINGNGNGVENGHQDEMATDGPSTSEAASAVIHPEDDNSL 196
            .|||:|.:.....|:|.|.|.|                .||.....|...||..  :..|||
Worm   133 IEKLSRKVETEDLRITTFPIRW----------------TDEDPVAEPVEDEANR--VFAEDD--- 176

  Fly   197 AMPMEN 202
            .||:.:
Worm   177 LMPLND 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
asf1	NP_001189131.1	ASF1_hist_chap	1..154	CDD:282572	78/151 (52%)
unc-85	NP_494837.2	ASF1_hist_chap	3..154	CDD:282572	78/150 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158710
Domainoid	1	1.000	183	1.000	Domainoid score	I2042
eggNOG	1	0.900	-	-		E1_COG5137
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8528
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2626
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54218
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001913
OrthoInspector	1	1.000	-	-		otm14649
orthoMCL	1	0.900	-	-		OOG6_101293
Panther	1	1.100	-	-	LDO	PTHR12040
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R94
SonicParanoid	1	1.000	-	-		X1264
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790