Protein Alignment Lon and lonp-2

DIOPT Version :10

• Sequence 1: NP_730435.2
• Gene: Lon / 40138
• FlyBaseID: FBgn0036892
• Length: 1024
• Species: Drosophila melanogaster
• Sequence 2: NP_499577.1
• Gene: lonp-2 / 176643
• WormBaseID: WBGene00013541
• Length: 773
• Species: Caenorhabditis elegans
• Alignment Length: 712
• Identity: 251/712 - (35%)
• Similarity: 405/712 - (56%)
• Gaps: 70/712 - (9%)

  Fly   298 KENVNQ-SAPSAQPVLIVEVENVKQPIYKQTEEVKALTQEIIKTLRDIITMNPLYRESLQQMLHQ 361
            :.|::: |.|:.   ::.:|.::.:.|..|....|.:|.      ..||..|.|    ..:...:
 Worm    94 RANIDKLSLPTC---IVSKVVDLNEAISNQNAIEKLVTG------AKIIASNSL----TDKFSRE 145

  Fly   362 NQRVVDNPIY--LCDLGAS-LSAGEPAELQKILEETDIPERLQLALTLLKKELELSRLQQKIGRE 423
            ...::|...|  |.||..| :......:|.:.|.......|:::.:..:.::.:.:.|:.|:...
 Worm   146 IYSLIDEKEYGKLADLCVSQMKFLGFMQLLEFLGANGTDARVEMCIKWMNEKKDANTLKLKVPNS 210

  Fly   424 VEEKVKQQHRKYILQEQLKVIKKELGIEKDDKDAIGEKYREKLKDKVVPEAIMTVIDEELTKLNF 488
            :|.......:|    .::..:|.::...::..:||  ::.:::.|:|.         .||.:|..
 Worm   211 LEASFPVDGKK----RKIPNVKNQVEQLEEKLNAI--EFSDEVSDRVY---------SELHRLKS 260

  Fly   489 LESHSSEFNVTRNYLDWLTSLPWGVISTENLCLEKATETLNDDHYGMEDIKKRILEFIAVSSLKG 553
            :.:..||:|:..|:|:.::||||...:.:::.|.||...|.:.|..|:|:|:|:||.:||..:..
 Worm   261 MNAQQSEYNILMNWLELVSSLPWNTSTIDDIELHKARTILTESHEAMDDVKERVLEHLAVCKMNN 325

  Fly   554 STQGKILCFHGPPGVGKTSIAKSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKLIQCL 618
            |.:|.||||.||||:|||||||:||.::.|::.|.|:||:.|.::|:|||||||.||||::|:.|
 Worm   326 SVKGMILCFTGPPGIGKTSIAKAIAESMGRKFQRVSLGGIRDESDIRGHRRTYVAAMPGRIIEAL 390

  Fly   619 KKTKIENPLVLIDEVDKIGKGYQGDPSSALLELLDPEQNANFLDHYLDVPVDLSRVLFICTANVI 683
            |..|..||:.|:|||||:..|.||.||:|||||||||||:.|.||||::|.|:|:::||.|||.|
 Worm   391 KTCKTNNPVFLLDEVDKLYSGNQGSPSAALLELLDPEQNSTFHDHYLNIPFDVSKIMFIATANDI 455

  Fly   684 DTIPEPLRDRMELIEMSGYVAEEKIAIARQYLMP-QAMKDCGLTDKHINISEDALNMLIRSYCRE 747
            |.:...||||:|:||||||..:||:.|...:|:. |..|.| ::..::.:...|:..:|..|..|
 Worm   456 DRLEPALRDRLEIIEMSGYSLKEKVKICENHLLTRQLTKHC-ISHDYVKLERQAIVAMIEEYTME 519

  Fly   748 SGVRNLQKHIEKVIRKVAFRVVK-----KEGEHFPV-------NADNLTTFLG----KQIFSSDR 796
            :|||.|::::..:.|.||.|:.:     ...:..||       :|.|:...|.    |::...::
 Worm   520 AGVRQLERNVGAICRNVALRLAEALNSDPGADVLPVMELPIQISASNIHKILKNKHMKRVKIVEK 584

  Fly   797 MYATTPVGVVMGLAWTAMGGSSLYIETSRRHIRQGAKTDPNTVAGSLHITGNLGDVMKESAQIAL 861
            | ...|.||..||:.|.:||..:.||.|:           :...|.:..||:||.|:|||    :
 Worm   585 M-RPLPAGVCFGLSVTTIGGRVMPIEASK-----------SKGTGKIVTTGHLGKVLKES----I 633

  Fly   862 TVARNFLYSLEPNNL---FLEQEHIHLHVPEGATPKDGPSAGITIITALVSLATGKPVRQDIAMT 923
            .||:.:| |.....|   .||.:.||:|:|.||..|||||||..:..|||||||..|:|.|.|:|
 Worm   634 LVAKGWL-SANSERLGLGTLEDQDIHVHLPAGAVNKDGPSAGTGLACALVSLATNIPLRSDAAVT 697

  Fly   924 GEVSLKGKVLPVGGIKEKTIAARRSGVNCLILPVDNKKDFEELPTYITDGLEVHFATTYEDV 985
            ||:||.|.|||:||:|||.:||:|.|:..::||..|::::.::...|...::|..|.|.|||
 Worm   698 GEISLTGHVLPIGGVKEKVLAAQREGLRRVVLPKSNEEEYLKMDEDIRLEMDVVLAETIEDV 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lon	NP_730435.2	lon	95..990	CDD:273258	251/712 (35%)
lonp-2	NP_499577.1	Lon	2..769	CDD:440234	251/712 (35%)