DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9372 and prss60.1

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	253	Identity:	91/253 - (35%)
Similarity:	127/253 - (50%)	Gaps:	27/253 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 CGITSRQFPRLTGGRPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCIYKKNKEDIFV 228
            ||:.... .|:.||..|....|||..:|........:|||.||....|||||||:.:.....:.|
Zfish    25 CGLAPLN-NRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAAHCLPRITTSSLLV 88

  Fly   229 RLGE-----YNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPP 288
            .||:     .||:.:|.|      ::.:.:|..||....:||||::.:..|..|:.||.|||:..
Zfish    89 FLGKTTQQGVNTYEINRT------VSVITVHPSYNNLTNENDIALLHLSSAVTFSNYIRPVCLAA 147

  Fly   289 VNEDW-SDRNAIVTGWGTQKFGG--PHSNILMEVNLPVWKQSDCRSSFVQ-HVPDTAMCAGFPEG 349
            .|..: :..::.:||||..:.|.  |...||.|..:||.....|.:.... .|.:..:|||..:|
Zfish   148 QNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMICAGLLQG 212

  Fly   350 GQDSCQGDSGGPL-----LVQLPNQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWI 402
            |:|:||||||||:     ||      ||..||.|||.||.....||:||||.:|..||
Zfish   213 GRDTCQGDSGGPMVSKQCLV------WVQSGITSWGYGCADPYSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9372	NP_649132.1	CLIP	87..132	CDD:197829
		Tryp_SPc	173..402	CDD:214473	87/242 (36%)
		Tryp_SPc	176..402	CDD:238113	86/239 (36%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	87/242 (36%)
		Tryp_SPc	34..267	CDD:238113	88/243 (36%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587671
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840