DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9372 and zgc:123295

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001032651.1	Gene:	zgc:123295 / 641564	ZFINID:	ZDB-GENE-051127-11	Length:	310	Species:	Danio rerio

Alignment Length:	241	Identity:	88/241 - (36%)
Similarity:	133/241 - (55%)	Gaps:	16/241 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 RLTGGRPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCIYKKNKEDIFVRLG-----E 232
            ::.||:.|....|||..:|........:|||.||....||:|||| ::.:...|.|:||     .
Zfish    35 KIVGGQNAGAGSWPWQVSLQSPTYGGHFCGGSLINKDWVLSAAHC-FQDSIGTIMVKLGLQSQSG 98

  Fly   233 YNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPPVNEDWSDRN 297
            .|.:.:.:|      :..::.|.:||..:.|||||:|::|.:..||.||.|||:......::...
Zfish    99 SNPYQITKT------VVQVINHPNYNNPSNDNDIALVKLDSSVTFNDYIEPVCLAAAGNTYAAGT 157

  Fly   298 -AIVTGWG-TQKFGGPHSNILMEVNLPVWKQSDCRSSFVQHVPDTAMCAG-FPEGGQDSCQGDSG 359
             :.||||| .........:||.||.:|:...|||:.::...:....:||| ..:||:||||||||
Zfish   158 LSWVTGWGKLSSAANQIPDILQEVEIPIVSHSDCKRAYPGEITSNMICAGLLDQGGKDSCQGDSG 222

  Fly   360 GPLLVQLPNQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWILAN 405
            || :|.....:|:..||||:|.||.:.|.||:|.||.:|.|||.::
Zfish   223 GP-MVSRNGSQWIQSGIVSFGRGCAEPGYPGVYARVSQYQDWITSS 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9372	NP_649132.1	CLIP	87..132	CDD:197829
		Tryp_SPc	173..402	CDD:214473	86/236 (36%)
		Tryp_SPc	176..402	CDD:238113	86/233 (37%)
zgc:123295	NP_001032651.1	Tryp_SPc	35..264	CDD:214473	86/236 (36%)
zgc:123295	NP_001032651.1	Tryp_SPc	36..264	CDD:238113	86/235 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587650
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840