DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG9372 and proz

DIOPT Version :9

Sequence 1:NP_649132.1 Gene:CG9372 / 40137 FlyBaseID:FBgn0036891 Length:408 Species:Drosophila melanogaster
Sequence 2:NP_001116189.1 Gene:proz / 496781 XenbaseID:XB-GENE-971425 Length:416 Species:Xenopus tropicalis


Alignment Length:460 Identity:103/460 - (22%)
Similarity:176/460 - (38%) Gaps:113/460 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 WALVILLGYIPQSTIAKTVSTDFLD-LLDFSDNDEFQW------GESENQVYENR--------TG 55
            :.|..|:.:|.|:.....:|::..: ::..|..|.|.:      |..|.:..|.|        |.
 Frog     8 FCLFSLMLFIHQAEAKVFLSSENANKVIQRSKRDNFIFIEELLKGNLERECLEERCSYEEARETF 72

  Fly    56 EN--RVVSFLSQHR------LN--KRQAPTSQLLENKDYGACSTPLGESGR-------------- 96
            ||  :...|.||:.      ||  |.|......:  :.| .||.|.|.:||              
 Frog    73 ENTEKTKQFWSQYHGGMKCSLNPCKNQGSCKDTI--RSY-ICSCPEGYTGRDCQFANNECHPDME 134

  Fly    97 --CRHIIYCRMPELKNDVWRLVSQLCIIEKSSIGICCTDQSTSNRFSPQVVTSADGDEPRIVNKP 159
              |:|  :|. |..:.|     |..|              |.:|.:..       |.:.:..:..
 Frog   135 DGCQH--FCH-PSYEAD-----SYSC--------------SCANGYKL-------GADEKSCHPE 170

  Fly   160 EQRGCGITSRQFPRLTGGR-PAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCI--YKK 221
            :...||........:|..| ..:.|.:||...:|......| |.||::::..|||.|.||  |  
 Frog   171 DPFACGQILNLEVSITKNRNHLQADIFPWQVPVLNSQKVQV-CSGVVLSESVVLTTASCITMY-- 232

  Fly   222 NKEDIFVRLGEYNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCM 286
              :..||..|......|.:.:.  .|:....:|:.|:.:..||:||::::....:|:....|:|:
 Frog   233 --DPYFVVAGVQQKSGLGQRQM--IRVKTKQVHMRYSEETGDNNIALLKLKEKIVFHNNSLPICI 293

  Fly   287 PPVNEDWSD------RNAIVTGWGTQKFGGPHSNILMEVNLPVWKQSD-CRSSFVQHVPDT-AMC 343
            |  .:|:::      ...:|:||.:.......:.|.::.......::: |..|.  :|..| .|.
 Frog   294 P--QKDFAENVLVPFNTGLVSGWKSSSEEEADALIPIQFYTKYTNRTEVCEQSL--NVTQTNRMF 354

  Fly   344 AGFPEGGQDSCQGDSGGPLLVQLPNQRWVTIGIV-SWGVGCGQRGRPGI-------YTRVDRYLD 400
            .|......|| :...||.|.|| .|..|...||: ||        :|.:       :|::.||..
 Frog   355 CGVSHEAIDS-ELSEGGHLAVQ-HNGVWFLGGIMGSW--------QPTLLNKGVFSFTKLSRYNM 409

  Fly   401 WILAN 405
            |:..|
 Frog   410 WLKQN 414

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9372NP_649132.1 CLIP 87..132 CDD:197829 13/60 (22%)
Tryp_SPc 173..402 CDD:214473 60/247 (24%)
Tryp_SPc 176..402 CDD:238113 59/244 (24%)
prozNP_001116189.1 GLA 22..85 CDD:214503 13/62 (21%)
EGF_CA 92..123 CDD:238011 11/33 (33%)
FXa_inhibition 136..167 CDD:373209 10/59 (17%)
Tryp_SPc 197..414 CDD:389826 58/237 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 168 1.000 Inparanoid score I4027
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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