DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9372 and flz

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001137622.1	Gene:	flz / 35902	FlyBaseID:	FBgn0286782	Length:	1693	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	111/416 - (26%)
Similarity:	181/416 - (43%)	Gaps:	117/416 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PQSTIAKTVSTDFL--------DLLDFSDNDEFQWGESENQVYENRTGENRVVSFLSQHRLNKRQ 72
            |...::.||.|..:        :::|..|.::.....|:|::.:..|        ||
  Fly  1359 PTRRVSSTVKTTTVSSARPADDEIVDEEDEEDVNPNPSDNEIDQGAT--------LS-------- 1407

  Fly    73 APTSQLLENKDYGACSTPLGESGRCRHIIYCRMPELKNDVWRLVSQLCIIEKSSIGICCTDQSTS 137
                      .||      |.:||..|                                   |||
  Fly  1408 ----------SYG------GANGRKIH-----------------------------------STS 1421

  Fly   138 NRF-SPQVVTSADGDEPRIVNKPEQRGCGITSR-QFPRLTGGRPAEPDEWPWMAALLQEGLPFVW 200
            ... :|.:...:...|           ||:... :..|:.||:.:....:||. .|::|.   .|
  Fly  1422 RTLPTPNLAFHSPSTE-----------CGVRPHVKSGRIVGGKGSTFGAYPWQ-VLVRES---TW 1471

  Fly   201 --------CGGVLITDRHVLTAAHCIYKKNKEDIFVR-----LGEYN-THMLNETRARDFRIANM 251
                    |||||||.|:|:|||||      :..|:.     :||:: :..|...|:....:..:
  Fly  1472 LGLFTKNKCGGVLITSRYVITAAHC------QPGFLASLVAVMGEFDISGDLESKRSVTKNVKRV 1530

  Fly   252 VLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPPVNEDWSDRNAIVTGWGTQKFGGPHSNIL 316
            ::|..|:|..::||:|::.:|....|:|:|.|:|||....|::.|.|.|||||..|:||...::|
  Fly  1531 IVHRQYDPATFENDLALLELDSPVQFDTHIVPICMPNDVADFTGRMATVTGWGRLKYGGGVPSVL 1595

  Fly   317 MEVNLPVWKQSDCRSSF-----VQHVPDTAMCAGFPEGGQDSCQGDSGGPLLVQLPNQRWVTIGI 376
            .||.:|:.:.|.|:..|     .:.:..:.:|||:..|.:|||:|||||||::|.|:.|:...|.
  Fly  1596 QEVQVPIIENSVCQEMFHTAGHNKKILTSFLCAGYANGQKDSCEGDSGGPLVLQRPDGRYELAGT 1660

  Fly   377 VSWGVGCGQRGRPGIYTRVDRYLDWI 402
            ||.|:.|.....||:|.|...|..|:
  Fly  1661 VSHGIKCAAPYLPGVYMRTTFYKPWL 1686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9372	NP_649132.1	CLIP	87..132	CDD:197829	4/44 (9%)
		Tryp_SPc	173..402	CDD:214473	86/247 (35%)
		Tryp_SPc	176..402	CDD:238113	85/244 (35%)
flz	NP_001137622.1	PRK14948	<272..452	CDD:237862
		PRK11633	<365..>439	CDD:236940
		PRK10263	<547..>1005	CDD:236669
		PHA03247	<792..1096	CDD:223021
		Tryp_SPc	1449..1689	CDD:238113	86/248 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457754
Domainoid	1	1.000	147	1.000	Domainoid score	I2768
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840