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Protein Alignment CG9372 and TMPRSS6

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_001275929.1	Gene:	TMPRSS6 / 164656	HGNCID:	16517	Length:	824	Species:	Homo sapiens

Alignment Length:	313	Identity:	99/313 - (31%)
Similarity:	150/313 - (47%)	Gaps:	63/313 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 CTDQSTSNRFSPQVVTSADG-DEPRIVNKPEQRGCGITSRQFP--RLTGGRPAEPDEWPWMAALL 192
            |.|:|...:.:||    .|| .:.|..:..|...||:   |.|  |:.||..:...||||.|:|.
Human   529 CEDRSCVKKPNPQ----CDGRPDCRDGSDEEHCDCGL---QGPSSRIVGGAVSSEGEWPWQASLQ 586

  Fly   193 QEGLPFVWCGGVLITDRHVLTAAHCIYKKNKEDIF-------VRLGE--YNTHMLNETRARDFRI 248
            ..|...  |||.||.||.|:|||||.    :||..       |.||:  .|:....|.   .|::
Human   587 VRGRHI--CGGALIADRWVITAAHCF----QEDSMASTVLWTVFLGKVWQNSRWPGEV---SFKV 642

  Fly   249 ANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMP-------PVNEDWSDRNAIVTGWGTQ 306
            :.::||..:...::|.|:|::::|...:.:..:.|||:|       |....|      :||||..
Human   643 SRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCW------ITGWGAL 701

  Fly   307 KFGG----------------------PHSNILMEVNLPVWKQSDCRSSFVQHVPDTAMCAGFPEG 349
            :.|.                      |.||.|.:|::.:..|..|...:...|....:|||:.:|
Human   702 REGALRADAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKG 766

  Fly   350 GQDSCQGDSGGPLLVQLPNQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWI 402
            .:|:|||||||||:.:..:.||...|:||||:|||:....|:|||:...:.||
Human   767 KKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWI 819

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.