DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9372 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	397	Identity:	120/397 - (30%)
Similarity:	183/397 - (46%)	Gaps:	81/397 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 WGESENQVYENRTGENRVV-----SFLSQHRLNKRQA--PTSQLLENKDYGACSTPLGESGRCRH 99
            |.:..:|. .|...|||.|     ||..|...::|:|  |..|...|:.||..:        |:.
  Rat   131 WCDGVSQC-PNGEDENRCVRLYGTSFTLQVYSSQRKAWYPVCQDDWNESYGRAA--------CKD 186

  Fly   100 IIYCRMPELKNDVWRLVSQLCIIEKSSIGICCTDQSTSNRFSPQVVTS-----------ADGDEP 153
            :.|      ||..:           ||.||  .|||.:..|....|::           :|....
  Rat   187 MGY------KNSFY-----------SSQGI--PDQSGATSFMKLNVSAGNVDLYKKLYHSDSCSS 232

  Fly   154 RIVNKPEQRGCGITS-RQFPRLTGGRPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHC 217
            |:|.......||:.| |:..|:.||..|.|.:|||..:|..:|:..  |||.:||...::|||||
  Rat   233 RMVVSLRCIECGVRSVRRQSRIVGGSTASPGDWPWQVSLHVQGIHV--CGGSIITPEWIVTAAHC 295

  Fly   218 IYKKNKEDI--------FVRLGEYNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRA 274
            :    :|.:        |..:.:.:. |...:|   .::..::.|.:|:.:..:||||::::...
  Rat   296 V----EEPLSSPRYWTAFAGILKQSL-MFYGSR---HQVEKVISHPNYDSKTKNNDIALMKLQTP 352

  Fly   275 TIFNTYIWPVCMPP-------VNEDWSDRNAIVTGWGTQKFGGPHSNILMEVNLPVWKQSDCRSS 332
            ..||..:.|||:|.       ..|.|      ::|||.....|..|::|....:|:.:.|.|.|.
  Rat   353 LAFNDVVKPVCLPNPGMMLDLAQECW------ISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSK 411

  Fly   333 FVQH--VPDTAMCAGFPEGGQDSCQGDSGGPLLVQLPNQRWVTIGIVSWGVGCGQRGRPGIYTRV 395
            ::.:  :....:||||.:|..|||||||||| ||.|.|:.|..||..|||.||.:..|||:|..|
  Rat   412 YIYNNLITPAMICAGFLQGSVDSCQGDSGGP-LVTLKNEIWWLIGDTSWGSGCAKAYRPGVYGNV 475

  Fly   396 DRYLDWI 402
            ..:.|||
  Rat   476 TVFTDWI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9372	NP_649132.1	CLIP	87..132	CDD:197829	8/44 (18%)
		Tryp_SPc	173..402	CDD:214473	81/245 (33%)
		Tryp_SPc	176..402	CDD:238113	80/242 (33%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060	5/16 (31%)
		SRCR_2	152..247	CDD:292133	28/121 (23%)
		Tryp_SPc	253..482	CDD:214473	81/245 (33%)
		Tryp_SPc	254..485	CDD:238113	82/246 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910