DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9372 and Prss29

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	NP_444490.2	Gene:	Prss29 / 114662	MGIID:	2149952	Length:	279	Species:	Mus musculus

Alignment Length:	271	Identity:	79/271 - (29%)
Similarity:	128/271 - (47%)	Gaps:	43/271 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 GCGITSRQFP-------RLTGGRPAEPDEWPWMAALLQEGLPFVW------CGGVLITDRHVLTA 214
            ||.|.....|       .:.||..|...:|||..:|  ....:.|      |||.:|..:.||||
Mouse    13 GCSIAGTPAPGPEGVLMGIVGGHSAPQGKWPWQVSL--RIYRYYWAFWVHNCGGSIIHPQWVLTA 75

  Fly   215 AHCIYKKNKE-DIF-VRLGEYNTHMLNETRARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIF 277
            ||||.:::.: .:| :|:||...:...|.    ..::.:::|.|:......:|:|::::..:...
Mouse    76 AHCIRERDADPSVFRIRVGEAYLYGGKEL----LSVSRVIIHPDFVHAGLGSDVALLQLAVSVQS 136

  Fly   278 NTYIWPVCMPPVNEDWSDRNAI-VTGWGTQKFGGPHSNI-----LMEVNLPVWKQSDCRSSF--- 333
            ...:.||.:|..:.:.:.::.. |||||..   ..|.::     |.:|.:.:...|.|...:
Mouse   137 FPNVKPVKLPSESLEVTKKDVCWVTGWGAV---STHRSLPPPYRLQQVQVKIIDNSLCEEMYHNA 198

  Fly   334 VQH-------VPDTAMCAGFPEGGQDSCQGDSGGPLLVQLPNQRWVTIGIVSWGVGCGQRGRPGI 391
            .:|       :....:|||  ..|||||.|||||||:..:... |..:|:||||.||..|..||:
Mouse   199 TRHRNRGQKLILKDMLCAG--NQGQDSCYGDSGGPLVCNVTGS-WTLVGVVSWGYGCALRDFPGV 260

  Fly   392 YTRVDRYLDWI 402
            |.||..:|.||
Mouse   261 YARVQSFLPWI 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9372	NP_649132.1	CLIP	87..132	CDD:197829
		Tryp_SPc	173..402	CDD:214473	73/252 (29%)
		Tryp_SPc	176..402	CDD:238113	73/249 (29%)
Prss29	NP_444490.2	Tryp_SPc	31..274	CDD:238113	75/253 (30%)
Prss29	NP_444490.2	Tryp_SPc	31..271	CDD:214473	73/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840