DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9372 and zgc:165423

DIOPT Version :9

Sequence 1:	NP_649132.1	Gene:	CG9372 / 40137	FlyBaseID:	FBgn0036891	Length:	408	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	295	Identity:	99/295 - (33%)
Similarity:	146/295 - (49%)	Gaps:	35/295 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 WRLVSQLCIIEKSSIGICCTDQSTSNRFSPQVVTSADGDEPRIVNKPEQRGCGITSRQFPRLTGG 177
            |:| |.||::...|.|..|         .|.....|.|..|  :|              .::.||
Zfish     3 WKL-SLLCVVTLLSTGCDC---------QPTQSPPACGKAP--LN--------------TKIVGG 41

  Fly   178 RPAEPDEWPWMAALLQEGLPFVWCGGVLITDRHVLTAAHCI-YKKNKEDIFVRLGEYNTHMLNET 241
            ..|....|||.|:|.:.|..|  |||.||:|:.:|:||||. ...|..|..|.||..:..:.|..
Zfish    42 TNASAGSWPWQASLHESGSHF--CGGSLISDQWILSAAHCFPSNPNPSDYTVYLGRQSQDLPNPN 104

  Fly   242 RARDFRIANMVLHIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPPVNEDWSDRNAIVTGWGTQ 306
            .... .::.:::|..|....:|||:|::.:.....|:.||.|||:......:.:....:|||||.
Zfish   105 EVSK-SVSQVIVHPLYQGSTHDNDMALLHLSSPVTFSNYIQPVCLAADGSTFYNDTMWITGWGTI 168

  Fly   307 KFGG--PHSNILMEVNLPVWKQSDCRSSF--VQHVPDTAMCAGFPEGGQDSCQGDSGGPLLVQLP 367
            :.|.  |...||.|||:|:...:.|...:  ...:.:..||||..:||:||||||||||::::..
Zfish   169 ESGVSLPSPQILQEVNVPIVGNNLCNCLYGGGSSITNNMMCAGLMQGGKDSCQGDSGGPMVIKSF 233

  Fly   368 NQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWI 402
            | .||..|:||:|.||.....||:|.||.:|.:||
Zfish   234 N-TWVQAGVVSFGKGCADPNYPGVYARVSQYQNWI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9372	NP_649132.1	CLIP	87..132	CDD:197829	7/18 (39%)
		Tryp_SPc	173..402	CDD:214473	84/233 (36%)
		Tryp_SPc	176..402	CDD:238113	84/230 (37%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	84/233 (36%)
		Tryp_SPc	38..269	CDD:238113	86/234 (37%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587672
Domainoid	1	1.000	191	1.000	Domainoid score	I3175
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840