DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Taf6 and TAFII59

DIOPT Version :9

Sequence 1:	NP_524161.2	Gene:	Taf6 / 40134	FlyBaseID:	FBgn0010417	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	NP_001030969.1	Gene:	TAFII59 / 839370	AraportID:	AT1G04950	Length:	549	Species:	Arabidopsis thaliana

Alignment Length:	580	Identity:	192/580 - (33%)
Similarity:	284/580 - (48%)	Gaps:	110/580 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SSISAESMKVIAESIGVGSLSDDAAKELAEDVSIKLKRIVQDAAKFMNHAKRQKLSVRDIDMSLK 83
            |.:..|:::|||:|||:.:|..:||..||.||..:::.|:|:|.|.|.|:||..|:..|:|.:|.
plant     2 SIVPKETVEVIAQSIGITNLLPEAALMLAPDVEYRVREIMQEAIKCMRHSKRTTLTASDVDGALN 66

  Fly    84 VRNVEPQYGFVAKDFIPFRFASG-GGRELHFTEDKEIDLGEITSTNSVKIPLDLTLRSHWFVVEG 147
            :|||||.|||.:..  ||||... |.|:|.:|:|:|:|..::......|.|||..:..||..:||
plant    67 LRNVEPIYGFASGG--PFRFRKAIGHRDLFYTDDREVDFKDVIEAPLPKAPLDTEIVCHWLAIEG 129

  Fly   148 VQPTVPENPPPLSKDSQLLDSVNPVIKMDQGLNKDAAGKPTTGKIHKLKNVETIHVKQLATHELS 212
            |||.:|||.|        |:.:.               .|...|||:.|:...|.|:....|.||
plant   130 VQPAIPENAP--------LEVIR---------------APAETKIHEQKDGPLIDVRLPVKHVLS 171

  Fly   213 VEQQLYYKEITEACVG-SDEPRRGEALQSLGSDPGLHEMLPRMCTFIAEGVKVNVVQNNLALLIY 276
            .|.|||:::|.|..:. |:.|...|||.||.||.|||.::|....|||:.|...:  |:..||..
plant   172 RELQLYFQKIAELAMSKSNPPLYKEALVSLASDSGLHPLVPYFTNFIADEVSNGL--NDFRLLFN 234

  Fly   277 LMRMVRALLDNPSLFLEKYLHELIPSVMTCIVSKQLCMRPELDNHWALRDFASRLMAQICKNFNT 341
            ||.:||:||.||.:.:|.|||:|:|||:||:||::|..| ..||||.|||||:.|::.|||.:.|
plant   235 LMHIVRSLLQNPHIHIEPYLHQLMPSVVTCLVSRKLGNR-FADNHWELRDFAANLVSLICKRYGT 298

  Fly   342 LTNNLQTRVTRIFSKALQNDKTHLSSLYGSIAGLSELGGEVIKVFIIPRLKFISERIEPHLLGTS 406
            :...||:|:||....||.:.|..|:..||:|.||:.||..|:::.|:..|:.....:||.|....
plant   299 VYITLQSRLTRTLVNALLDPKKALTQHYGAIQGLAALGHTVVRLLILSNLEPYLSLLEPELNAEK 363

  Fly   407 ISNTDK------------TAAG---HIRAMLQKCCPPILRQMRSAPDTAEDYKNDFGFLGPSLCQ 456
            ..|..|            .|||   |.|.   |..||:                      ||
plant   364 QKNQMKIYEAWRVYGALLRAAGLCIHGRL---KIFPPL----------------------PS--- 400

  Fly   457 AVVKVRNAPASSIVTL---SSNTINTAPITSAAQTATTIGRVSMPTTQRQGSPGVSSLPQIRAIQ 518
                    |:.|.:..   ....|:|.|...         ::|:.:::.|.       ||.|.|.
plant   401 --------PSPSFLHKGKGKGKIISTDPHKR---------KLSVDSSENQS-------PQKRLIT 441

  Fly   519 ANQPAQKFVIVTQNSPQQGQAKV-----VRRGSSPHSVVLSAASNAASASNSNSSSSGSL 573
            .:.|..     ..:..|.|.|.:     |...:.|.:.|..::|..||.:|.:.|.:|.:
plant   442 MDGPDG-----VHSQDQSGSAPMQVDNPVENDNPPQNSVQPSSSEQASDANESESRNGKV 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf6	NP_524161.2	TAF6	22..383	CDD:173968	149/362 (41%)
TAFII59	NP_001030969.1	TAF6	1..383	CDD:227426	158/408 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	139	1.000	Domainoid score	I1550
eggNOG	1	0.900	-	-		E1_COG5095
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I946
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384329at2759
OrthoFinder	1	1.000	-	-		FOG0003125
OrthoInspector	1	1.000	-	-		otm3373
orthoMCL	1	0.900	-	-		OOG6_103103
Panther	1	1.100	-	-	O	PTHR10221
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2507
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830