Protein Alignment Taf6 and Taf6

DIOPT Version :10

• Sequence 1: NP_524161.2
• Gene: Taf6 / 40134
• FlyBaseID: FBgn0010417
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_011239238.1
• Gene: Taf6 / 21343
• MGIID: 109129
• Length: 689
• Species: Mus musculus
• Alignment Length: 633
• Identity: 263/633 - (41%)
• Similarity: 374/633 - (59%)
• Gaps: 69/633 - (10%)

  Fly    16 LYGSSISAESMKVIAESIGVGSLSDDAAKELAEDVSIKLKRIVQDAAKFMNHAKRQKLSVRDIDM 80
            |..:.:.:|||||:|||:|:..:.::..:.|.::||.::|.|.|||.|||:..|||||:..|||.
Mouse     9 LSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQKLTTSDIDY 73

  Fly    81 SLKVRNVEPQYGFVAKDFIPFRFASGGGRELHFTEDKEIDLGEITSTNSVKIPLDLTLRSHWFVV 145
            :||::||||.|||.|::||||||||||||||:|.|:||:||.:|.:|...::|||:.|::||..:
Mouse    74 ALKLKNVEPLYGFHAQEFIPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSI 138

  Fly   146 EGVQPTVPENPPPLSKDSQLLDSVNPVIKMDQGLNKD------------AAGKPTTGKIHKLKNV 198
            ||.||.:||||||..|:.|..::..|:.....|..:|            |.||....|...|...
Mouse   139 EGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAADGKGKEKKAPPLLEG 203

  Fly   199 ETIHVKQLATHELSVEQQLYYKEITEACVGSDEPRRGEALQSLGSDPGLHEMLPRMCTFIAEGV- 262
            ....:|..:.|||||||||||||||||||||.|.:|.|||||:.:||||::||||..|||:|||
Mouse   204 APFRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFSTFISEGVR 268

  Fly   263 -----------------KVNVVQNNLALLIYLMRMVRALLDNPSLFLEKYLHELIPSVMTCIVSK 310
                             :|.....||.    ...:|...|..|.|   ..:|||||:|||||||:
Mouse   269 ELGKDRPMMRLQGRGMTRVRGPSGNLT----TGGLVSDSLTGPGL---SQVHELIPAVMTCIVSR 326

  Fly   311 QLCMRPELDNHWALRDFASRLMAQICKNFNTLTNNLQTRVTRIFSKALQNDKTHLSSLYGSIAGL 375
            |||:||::||||||||||:||:|||||:|:|.|||:|:|:|:.|:|:..::||..::.|||||||
Mouse   327 QLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDEKTPWTTRYGSIAGL 391

  Fly   376 SELGGEVIKVFIIPRLKFISERIEPHLLGTSISNTDKTAAGHIRAMLQKCCPPILRQMRSAPDTA 440
            :|||.:|||..|:|||:...|||...|.|..:||.|:..|.|::::|.|.|.|:|.::|..||..
Mouse   392 AELGHDVIKTLILPRLQQEGERIRSVLDGPVLSNIDRIGADHVQSLLLKHCAPVLAKLRPPPDNQ 456

  Fly   441 EDYKNDFGFLGPSLCQAVVKVRNAPASSIVTLSSNTINTAPITSAAQTAT-TIGRVSMPTTQRQG 504
            :.|:.:||.|||.||..|||.|...|     |.:..:|...:|......| |:.:...|..:..|
Mouse   457 DAYRGEFGSLGPLLCSHVVKARAQAA-----LQAQQVNRTTLTITQPRPTLTLSQAPQPGPRTPG 516

  Fly   505 ---SPGVSSLP-----QIRAI---QANQPAQKFVIVTQNSPQQGQAKVVRRGSSPHSVVLSAASN 558
               .||..:||     ..||.   |.:.|..||::::.:|           .:|....|||.:::
Mouse   517 LLKVPGSIALPVQTLVSARAAAPPQPSPPPTKFIVMSSSS-----------SASSTQQVLSLSTS 570

  Fly   559 AASASNSNSSSSGSLLAAAQ---RSSDNVCVIAGSEAPAVDGITVQSF 603
            |..:.::.:|...:.:.:.|   :..........|.|||..| :||.:
Mouse   571 APGSGSTTTSPVTTTVPSVQPIVKLVSTATTAPPSTAPAGSG-SVQKY 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Taf6	NP_524161.2	TAF6	22..393	CDD:227426	199/400 (50%)
		TAF6C	209..425	CDD:381749	123/233 (53%)
		HEAT repeat	213..244	CDD:381749	24/30 (80%)
		HEAT repeat	251..286	CDD:381749	13/52 (25%)
		HEAT repeat	296..339	CDD:381749	34/42 (81%)
		HEAT repeat	346..378	CDD:381749	14/31 (45%)
		HEAT repeat	380..424	CDD:381749	18/43 (42%)
Taf6	XP_011239238.1	HFD_TAF6	12..77	CDD:467055	29/64 (45%)
		TAF6C	214..441	CDD:381749	119/244 (49%)
		HEAT repeat	218..249	CDD:381749	20/30 (67%)
		HEAT repeat	256..288	CDD:381749	7/31 (23%)
		HEAT repeat	312..355	CDD:381749	27/42 (64%)
		HEAT repeat	362..394	CDD:381749	20/31 (65%)
		HEAT repeat	396..440	CDD:381749	15/43 (35%)