DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Taf6 and taf6

DIOPT Version :9

Sequence 1:	NP_524161.2	Gene:	Taf6 / 40134	FlyBaseID:	FBgn0010417	Length:	606	Species:	Drosophila melanogaster
Sequence 2:	XP_031755374.1	Gene:	taf6 / 100493467	XenbaseID:	XB-GENE-5774698	Length:	670	Species:	Xenopus tropicalis

Alignment Length:	614	Identity:	290/614 - (47%)
Similarity:	400/614 - (65%)	Gaps:	50/614 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SSSMLYGSSIS-----AESMKVIAESIGVGSLSDDAAKELAEDVSIKLKRIVQDAAKFMNHAKRQ 71
            ||.|..|..|.     :|||||||||:||..:|::..:.||::||.::|.:.|||.|||:..|||
Frog    46 SSIMAEGKKIGNTLLPSESMKVIAESVGVSQMSEETCQMLAQEVSFRIKEVTQDALKFMHVGKRQ 110

  Fly    72 KLSVRDIDMSLKVRNVEPQYGFVAKDFIPFRFASGGGRELHFTEDKEIDLGEITSTNSVKIPLDL 136
            ||:..|||.:||::||||.|||.||:|:|||:||||||||||.|:||:||.:|.||...::|||:
Frog   111 KLTPNDIDAALKLKNVEPIYGFHAKEFLPFRYASGGGRELHFYEEKEVDLSDIISTPLPRVPLDV 175

  Fly   137 TLRSHWFVVEGVQPTVPENPPPLSKDSQLLDSVNPV--IKMDQ------GLNKDAAGKPTTGKIH 193
            ::::||..:|||||.:||||||::|:.|..::..|:  :|..|      |..:.|......||..
Frog   176 SIKAHWLSIEGVQPAIPENPPPVTKEQQKSEATEPLKAVKPGQEEGGLKGKGQGAGAAEGKGKEK 240

  Fly   194 KLKNVE--TIHVKQLATHELSVEQQLYYKEITEACVGSDEPRRGEALQSLGSDPGLHEMLPRMCT 256
            |...:|  .:.:|..:.|||||||||||||||||||||.|.:|.|||||:.:||||::||||..|
Frog   241 KTPILEGAPLKLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPGLYQMLPRFST 305

  Fly   257 FIAEGVKVNVVQNNLALLIYLMRMVRALLDNPSLFLEKYLHELIPSVMTCIVSKQLCMRPELDNH 321
            ||:|||:||||||||||||||||||:||:|||:|:||||||||||:|||||||:|||:||::|||
Frog   306 FISEGVRVNVVQNNLALLIYLMRMVKALMDNPTLYLEKYLHELIPAVMTCIVSRQLCLRPDVDNH 370

  Fly   322 WALRDFASRLMAQICKNFNTLTNNLQTRVTRIFSKALQNDKTHLSSLYGSIAGLSELGGEVIKVF 386
            |||||||:||:|||||||:|.|||:|:|:|:.|:|...:|:|..::.|||||||:|||.:|:|..
Frog   371 WALRDFAARLIAQICKNFSTTTNNIQSRITKTFTKTWVDDRTPWTTRYGSIAGLAELGPDVVKTL 435

  Fly   387 IIPRLKFISERIEPHLLGTSISNTDKTAAGHIRAMLQKCCPPILRQMRSAPDTAEDYKNDFGFLG 451
            |:|||....||:...:.|..|||.||..|.|::::|.|...|:|.::||:||:.:.|:.|:|:||
Frog   436 IVPRLAVEGERLRSVMEGPVISNIDKIGADHVQSLLLKHSAPVLVKLRSSPDSPDAYRADYGYLG 500

  Fly   452 PSLCQAVVKVRNAPASSIVTLSSNTIN--TAPITSAAQTATTIGRVSMPTTQRQGSPGVSSLPQI 514
            |:||..|:|.|...|     |....:|  |..:|....|.|.....|...|....:|.:..:|..
Frog   501 PTLCTHVLKARAQSA-----LQGPQVNRTTLTVTQPRPTLTLSQPSSGSLTPSPRTPSIIKVPSS 560

  Fly   515 RAIQANQPAQKFVIVTQNSPQQGQAKVVRRGSSPHSVVLSAASNAASASNSNSSSSGSLLAAAQR 579
            ..:    |.|..|.....:|.|        .|.|.:..:..:|..:|.:...:.|||.
Frog   561 LTL----PVQTLVSARPATPTQ--------PSPPPTKYIVVSSAGSSGTQVLTPSSGP------- 606

  Fly   580 SSDNVC---------VIAGSEAPAVDGIT 599
            ||...|         :::|.::..|.|.|
Frog   607 SSSTPCPPGVQPIVKLVSGGQSSGVGGNT 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Taf6	NP_524161.2	TAF6	22..383	CDD:173968	220/375 (59%)
taf6	XP_031755374.1	TAF6	58..452	CDD:227426	228/393 (58%)
taf6	XP_031755374.1	TAF6C	258..474	CDD:381749	145/215 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	272	1.000	Domainoid score	I1777
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7561
Inparanoid	1	1.050	533	1.000	Inparanoid score	I1186
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384329at2759
OrthoFinder	1	1.000	-	-		FOG0003125
OrthoInspector	1	1.000	-	-		oto104359
Panther	1	1.100	-	-	LDO	PTHR10221
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2507
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160