Protein Alignment ash1 and SET4

DIOPT Version :9

• Sequence 1: NP_001246834.1
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Sequence 2: NP_012430.1
• Gene: SET4 / 853339
• SGDID: S000003641
• Length: 560
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 98/496 - (19%)
• Similarity: 185/496 - (37%)
• Gaps: 131/496 - (26%)

  Fly  1656 LCSPRNIKTRGLTQAVHDPELEKMAKMAVVLRDICSAMETLKMSDLLTTVSSKKK-----KPIKT 1715
            :.||.::.:|.:.|.                |...:..:.:..|...::.||..|     .|:
Yeast     1 MTSPESLSSRHIRQG----------------RTYTTTDKVISRSSSYSSNSSMSKDYGDHTPL-- 47

  Fly  1716 TLSGKLGSTAATSK-VEFRSIQAQVEQGHYKTPQEFDDHMQQLFVEAKQQHGDDEGKEKALQSLK 1779
            ::|.....|..:.: :..|:.......|  .||.....:.:.:|     .|....|..|..
Yeast    48 SVSSAASETLPSPQYMPIRTFNTMPTAG--PTPLHLFQNDRGIF-----NHHSSSGSSKTA---- 101

  Fly  1780 DSYEQQKIASYVQLVEILGDSESLQSFKPKEVLSSEEEPGKIAVKKSPGAKERDSPIVPLKVTPP 1844
             |..::.||:.|.|.     :.:...|..|:  .::::..|::|..:..:||.       |:||
Yeast   102 -STNKRGIAAAVALA-----TAATIPFPLKK--QNQDDNSKVSVTHNESSKEN-------KITP- 150

  Fly  1845 PLLPIEASPDEDVIRCICGL--YKDEGLMIQCSKCMVWQHTEC---TKADIDADNYQCERCE--- 1901
               .:.|..::....||||.  .||| |.|||:||..|||..|   .|:|....::.|:||:
Yeast   151 ---SMRAEDNKPKNGCICGSSDSKDE-LFIQCNKCKTWQHKLCYAFKKSDPIKRDFVCKRCDSDT 211

  Fly  1902 ------------PREVDREIPLEEFTEEGHRYYLSLMRGDLQVRQGDAVYVLRDIPIKDESGKVL 1954
                        ||::..| .|.:|:.     .::....:....| .:|..:.:.|.|.:.....
Yeast   212 KVQVNQVKPMIFPRKMGDE-RLFQFSS-----IVTTSASNTNQHQ-QSVNNIEEQPKKRQLHYTA 269

  Fly  1955 PTKKHTYETIGAIDYQECDIFRVEHLWKNELGKRFIFGHHFLRP--HETFHEPSRRFYPNEVVRV 2017
            ||.:::                 ..:.|....::.:...|||:|  :|........|   :.:.:
Yeast   270 PTTENS-----------------NSIRKKLRQEKLVVSSHFLKPLLNEVSSSNDTEF---KAITI 314

  Fly  2018 SLYEVVPIELVIGR----CWVLDRTTFCKGRPMECNDEDHCYICELRVDKTA--RFFSKAKANHP 2076
            |.|:...:::.|..    .||:            |::.:.....::.|.|::  |.|....|:
Yeast   315 SEYKDKYVKMFIDNHYDDDWVV------------CSNWESSRSADIEVRKSSNERDFGVFAAD-- 365

  Fly  2077 ACTKSYAFRKFPEKIKISKSYAPHDVDPS----LLKTRKQK 2113
            :|.|....:::..||...|:|   ..||:    |:.|.|.|
Yeast   366 SCVKGELIQEYLGKIDFQKNY---QTDPNNDYRLMGTTKPK 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ash1	NP_001246834.1	AWS	1340..1388	CDD:197795
		SET	1392..1512	CDD:214614
		Bromo_ASH1	1680..1787	CDD:99955	17/112 (15%)
		PHD_ASH1L	1858..1900	CDD:277023	20/46 (43%)
		BAH_polybromo	1929..2073	CDD:240068	23/151 (15%)
SET4	NP_012430.1	SET	16..526	CDD:225491	94/465 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030