Protein Alignment ash1 and LOC4577143

DIOPT Version :10

• Sequence 1: NP_524160.2
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Sequence 2: XP_313355.5
• Gene: LOC4577143 / 4577143
• VectorBaseID: AGAMI1_013464
• Length: 851
• Species: Anopheles gambiae
• Alignment Length: 970
• Identity: 215/970 - (22%)
• Similarity: 319/970 - (32%)
• Gaps: 356/970 - (36%)

  Fly   805 SALTPKKRHLLEQPTSVSGAGSSASNSPLRIVVDNNSISGGKLLDISP---SSLCSLKQQRRGGA 866
            |..|..:.||.:|                    |.:.:...||..:||   |...::.....|..
Mosquito     9 STATTGQPHLQQQ--------------------DLSKLDITKLTPLSPEVISRQATINIGTIGHV 53

  Fly   867 AKQKVSAAKDLVQLQSPAGSYPPPGVFEPSVELEIQIPLSKLNESVITKAEVESPLLSALDIKED 931
            |..|.:..|.:..:|:..        |:..:|..|.|.|..|::|.|.            .::.|
Mosquito    54 AHGKSTVVKAISGVQTVR--------FKNELERNITIKLENLSKSFIE------------TLQSD 98

  Fly   932 TKKEVGQRVVETLLHKTGGNLLLKRKRKKINRTGFPTVRRKKRKVSVEQQTTAVIDEHEPEFDPD 996
            .|      |:|..|||      :..:.|.....|                 |:..::|.|.
Mosquito    99 AK------VMEAYLHK------MHEQYKSPYNHG-----------------TSHSNKHTPS---- 130

  Fly   997 DEPLQSLRETRSSNNVNVQAAPNPPLDCERVPQAGEARETFVARTNQKAPRLSVVALERLQRPQT 1061
                   |:.:.|.| .:|.:|....:.:|:.|| :..:.|    :...|       ||:.:|..
Mosquito   131 -------RKRKLSPN-GLQTSPTNNGETQRMKQA-KIMDFF----HMSPP-------ERITQPSL 175

  Fly  1062 PARGRPRGRKPKNREQAEAA---------PQP---PPKSEPEIRPAKKR------GRQPKQP--- 1105
            .| .|.|.|    |:...||         |:|   |.:....|...||.      |.:...|
Mosquito   176 HA-SRERAR----RKSCPAAQGNFSGTHIPKPNGFPKRMSCSIDKVKKEVDESEDGSRFDVPTDT 235

  Fly  1106 ---VLEEPPPTPPPQQKKN-KMEPNIRLPDGID-----------PNTNFSCKIRLKRRKNLEAGT 1155
               .:.:...||   .|:| |:|.:...||.:.           |.|..|.|:        |.||
Mosquito   236 RLATINQEQATP---DKQNIKVECSDETPDAMSSSSQVENGTETPKTTASVKV--------ENGT 289

  Fly  1156 QPKKEKPVQPVT------------------------------VEE--IPPEIPVSQEE----IDA 1184
                :.||.||.                              ||.  :.|..|||::.    ::.
Mosquito   290 ----DTPVTPVARDNSNGLLKVMSAAKPSPKTSTPKTTASIKVENGTVSPATPVSRDSSKGLLNV 350

  Fly  1185 EAEAKRLDSIPT---EHDPLPASESHNPGPQDYASCSESSEDKASTTSLRK--LSKVKKTYLVA- 1243
            :..||.....|.   .:..|.|.:| .|..:.....|.|.:.|.|.|:.::  :..::...||.
Mosquito   351 KLAAKPSPKTPATGERNSSLSAGKS-TPKRKSTGGGSNSKQIKKSATTSKEYTVENIEDIQLVGN 414

  Fly  1244 ---------GLFSNHYKQSLMPPPAKVN-----------KKPGLEEQVGP--ASLLPPPPYCEKY 1286
                     |..|   |.:...|...||           :...|||.|.|  ..:...|.|.|..
Mosquito   415 SPFFLVKWLGYTS---KDNTWEPLNNVNSCAMLDSFLSAQMSLLEEWVEPLQEKIRSSPEYLESL 476

  Fly  1287 LRRTEMDFE------LPYD-----------------------IWWAYT----------------- 1305
            .|:....::      ..||                       ||...|
Mosquito   477 ERQGSKTYQEILLEHKEYDWDQLRADLIIMAKLWMNRGRNKLIWERITRLMCRELSYAKRCEQLE 541

  Fly  1306 ---------NSKLPTRNVV---------PSWNYRKIRTNVYAESVR-PNLAGFDHPT-CNCKN-Q 1349
                     |...||..||         |..|:..::.|:.||.:. ||    |.|. |.|.. .
Mosquito   542 ELRRFEKHINDHEPTLRVVVENEHDLDAPPNNFTYLQGNIPAEGISIPN----DPPVGCECNPCT 602

  Fly  1350 GEKSCLDNCL-NRMVYT--------------ECSPSNCPAGEKCRNQKIQRHAVAPGVERFMTAD 1399
            |..:|..... .|..|:              ||: ..|..|..|.|:.:|..... .:..|.|.:
Mosquito   603 GRSTCCGKLSEGRFAYSVKKRLLLQPGAPIFECN-KKCSCGPDCLNRVVQNGGKC-NLTLFKTPN 665

  Fly  1400 -KGWGVRTKLPIAKGTYILEYVGEVVTEKEFKQR------MASIYL-----NDTHHYCLHLDGGL 1452
             :||||||...|.:|.||.||.|||::..|.::|      :...||     |.|       |...
Mosquito   666 GRGWGVRTNTVIYEGQYISEYCGEVISYDEAEKRGREYDAVGRTYLFDLDFNGT-------DNPY 723

  Fly  1453 VIDGQRMGSDCRFVNHSCEPNCEMQKWSV------NGLSRMVLFAKRAIEEGEELTYDYNFSLFN 1511
            .:|..|.|:..||.||||:|||.:  |||      ..|.|:..||:|.||.|||||::|:..:
Mosquito   724 TLDAARYGNVTRFFNHSCDPNCGI--WSVWIDCLDPYLPRLAFFAQRRIEIGEELTFNYHAQV-- 784

  Fly  1512 PSEGQPCRCNTPQCRGVIGGKSQRVKPLP-------AVEAKP--SGEGLSGRNGRQRKQK 1562
                      :|....:.||......|:.       .||.||  :|:..:..||..|..|
Mosquito   785 ----------SPNNVSINGGSGGGGPPMDGDSSTGGVVEEKPAENGDKATTANGSVRNTK 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ash1	NP_524160.2	PHA03247	<1018..1281	CDD:223021	74/362 (20%)
		AWS	1340..1388	CDD:197795	15/64 (23%)
		SET_ASH1L	1391..1531	CDD:380951	53/157 (34%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068
LOC4577143	XP_313355.5	None