DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ash1 and cti6

DIOPT Version :9

Sequence 1:	NP_001246834.1	Gene:	ash1 / 40133	FlyBaseID:	FBgn0005386	Length:	2226	Species:	Drosophila melanogaster
Sequence 2:	NP_595212.1	Gene:	cti6 / 2539769	PomBaseID:	SPBC1685.08	Length:	424	Species:	Schizosaccharomyces pombe

Alignment Length:	180	Identity:	54/180 - (30%)
Similarity:	77/180 - (42%)	Gaps:	51/180 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1815 EEEPGKIAVKKSPGAKERDSPIVPLKVTPPPLLPIEASPDEDVIRCICGLYK------DEGLMIQ 1873
            |||..||  :|||    .|:|..| ..:.......|.|...:|.||:||:.:      |.||.||
pombe    13 EEESEKI--QKSP----VDTPHTP-NGSVSDNEENETSSTGEVTRCVCGIVESDDEASDGGLYIQ 70

  Fly  1874 CSKCMVWQHTECT----KADIDADNYQCERCEPREVDREIPLEEFTEEGHRYYLSLMRGDLQVRQ 1934
            |.:|.||||..|.    :::: .:.|.||.|.|              |.|:.| ...||..|.:
pombe    71 CDQCSVWQHGNCVGFADESEV-PEVYYCEICHP--------------EFHKVY-QRGRGAKQSK- 118

  Fly  1935 GDAVYVLRDIPIK----DESGKVLP---TKKHTYETI------GAIDYQE 1971
                |:....||:    :||....|   |||.:.:.:      .|:||:|
pombe   119 ----YLGNGKPIEASQTEESSSTPPSPATKKSSKQRLTMNSRDAALDYEE 164

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ash1	NP_001246834.1	AWS	1340..1388	CDD:197795
		SET	1392..1512	CDD:214614
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023	19/51 (37%)
		BAH_polybromo	1929..2073	CDD:240068	14/56 (25%)
cti6	NP_595212.1	PHD_SF	50..100	CDD:304600	19/50 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4489
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030