Protein Alignment ash1 and set-15

DIOPT Version :9

• Sequence 1: NP_001246834.1
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Sequence 2: NP_001370771.1
• Gene: set-15 / 187813
• WormBaseID: WBGene00020006
• Length: 611
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 134/599 - (22%)
• Similarity: 200/599 - (33%)
• Gaps: 192/599 - (32%)

  Fly  1069 GRKPKNREQAEAA-PQPPPKSEPEIRPAKKRGRQPKQPVLEEPPP-------------TPPPQQK 1119
            ||..:.|.....| .||..:|:.|...:||...|.|:.:.::|..             |.....:
 Worm    18 GRSFRKRSVTSLANEQPAKRSKTEGSDSKKLNNQMKRLMAKDPKKLSFNEATLLSELLTTCCTVE 82

  Fly  1120 KNKMEPNIRLPDGI----------DPNTNFS-CKIRLKRRKN-LEAGTQPKKEKPVQPVTVEEIP 1172
            :.|:.|. |...|.          |.|.|.. .|...|::.| ||..:  ||:|.......|
 Worm    83 RKKVIPK-RKGGGALRKSPVDFQNDENRNTKPIKSGRKKKDNLLEQAS--KKDKIAAKYRNE--- 141

  Fly  1173 PEIPVSQEEIDAEAEAKRL---DSIPTEHDPLPASESHNPGPQDYASCSE----SSEDKASTTSL 1230
                :....|.|..|.|::   .|..||.|.....:         |.||.    .|:.:.....:
 Worm   142 ----IFAHSIIANLEIKKILTKTSKATEKDLKLFLK---------AECSVRNAIKSDPELDGFYV 193

  Fly  1231 RKLSK-VKKTYL--VAGLFSNHYKQSL----MP----------------------PPAK---VNK 1263
            |...| :.||.|  :|.:..||...:.    ||                      ||.|   |.|
 Worm   194 RTCGKLINKTVLNTMADMMDNHMATTRLLWNMPRHEFPVDFHEKFVDFALNVSYTPPKKRIFVEK 258

  Fly  1264 KPGLEEQVGPASLLPPPPYCEKYLRRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKIRTNVY 1328
            |. .|:.:...:.:|         ..|.....|.....:.||.     ||||....|.::.. :.
 Worm   259 KL-FEKSISTFTDIP---------GETHRTISLGNTFVYKYTE-----RNVVDVEKYPELHA-LT 307

  Fly  1329 AESVRPNLAGFDHPTCNCKNQGE-KSCLDN----CL-------------NRMVYTE--------- 1366
            .|:.|||    :...|.|.:.|. |.|.:|    |.             |..:.|:
 Worm   308 EEAERPN----NVIRCECCSSGSIKKCWNNPDCFCFQMNLKLRKEQDPKNNKLLTDFSTFDPVFI 368

  Fly  1367 -------------CSPSNCPAGEKCRNQKIQRHAVAP--GVERFMTADK----GWGVRTKLPIAK 1412
                         || .||..|.||.|    ...:.|  .:.:|....|    |:.:||...|..
 Worm   369 RERNHFFDTIGFACS-ENCACGGKCTN----NITLLPEKNINKFEIYRKNEIMGFAIRTLNSIPA 428

  Fly  1413 GTYILEYVGEVVTEKEF------KQRMASIYLNDTHHYCLH---------------------LDG 1450
            ||.::|:.||::   :|      .|..|...:|:.|:  ||                     |..
 Worm   429 GTPVMEFTGELM---DFDILDNIDQDYAFEIVNEAHN--LHETLPNFNKRWSENFKSSLKKQLAR 488

  Fly  1451 GLVIDGQRMGSDCRFVNHSCEPNCEMQKWSVNGLS----RMVLFAKRAIEEGEELTYDYNFSLFN 1511
            ...::.:|:|:..|...|||:||..|.:....|.|    :::|.....|..|.|||:||.....|
 Worm   489 PWFVNPKRIGNVARICCHSCQPNMAMVRVFQKGFSPAHCKLLLVTLEDIFPGVELTFDYGPGYLN 553

  Fly  1512 PSEGQPCRCNTPQC 1525
            ..:| .|.|....|
 Worm   554 ELKG-GCLCERIGC 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ash1	NP_001246834.1	AWS	1340..1388	CDD:197795	17/87 (20%)
		SET	1392..1512	CDD:214614	38/154 (25%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068
set-15	NP_001370771.1	SET	405..554	CDD:214614	38/153 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165851
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840