Protein Alignment ash1 and set-11

DIOPT Version :10

• Sequence 1: NP_524160.2
• Gene: ash1 / 40133
• FlyBaseID: FBgn0005386
• Length: 2226
• Species: Drosophila melanogaster
• Sequence 2: NP_001364763.1
• Gene: set-11 / 185242
• WormBaseID: WBGene00018023
• Length: 278
• Species: Caenorhabditis elegans
• Alignment Length: 270
• Identity: 83/270 - (30%)
• Similarity: 120/270 - (44%)
• Gaps: 46/270 - (17%)

  Fly  1283 CEKYL------RRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKIRTNVYAESVRPNL----A 1337
            ||:::      .|..||..|       :.|.|..:|.:       .:...:...|..|..    |
 Worm    28 CERFVVPVYSNPRFFMDSSL-------FENFKYTSRII-------DVAGQLACRSASPTFMCQCA 78

  Fly  1338 GFDHPTCNCKNQ--GEKSCLDNCLNRMVYT--ECSPSNCPAGEKCRNQKIQRHAVAPGVERFMTA 1398
            |.....|.|.:.  ||...::|....|..|  ||: ..|.....|.|:..|:.|:.| ||.| ..
 Worm    79 GQCSTNCECSSGVFGEGGTVENMELLMWDTVRECN-EYCNCALWCGNRVAQKGAMYP-VEIF-AR 140

  Fly  1399 DK--GWGVRTKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDTHHYCLHLDGG--LVIDGQRM 1459
            |.  |||||..:.||.||:|.||.||::.::|...|..|.:|.:|.      .|.  |.||.:..
 Worm   141 DPWCGWGVRASVDIAFGTFIGEYAGELIDDEEAMDRHDSTFLFETK------VGSETLTIDAKYS 199

  Fly  1460 GSDCRFVNHSCEPNCEMQ--KWSVN--GLSRMVLFAKRAIEEGEELTYDYNFSLFNPSEGQPCRC 1520
            |:..||:||||.||.::.  .|..:  .|..|..|..:||.:|||||.||..:.: .::..||.|
 Worm   200 GNYTRFINHSCAPNVKVANISWDYDKIQLIHMCFFTDKAIRKGEELTIDYGEAWW-ANKKFPCLC 263

  Fly  1521 NTPQCRGVIG 1530
            .:.:||...|
 Worm   264 KSSECRYQFG 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ash1	NP_524160.2	PHA03247	<1018..1281	CDD:223021
		AWS	1340..1388	CDD:197795	13/51 (25%)
		SET_ASH1L	1391..1531	CDD:380951	55/148 (37%)
		Bromo_ASH1	1680..1787	CDD:99955
		PHD_ASH1L	1858..1900	CDD:277023
		BAH_polybromo	1929..2073	CDD:240068
set-11	NP_001364763.1	PreSET	21..117	CDD:128744	22/103 (21%)
		SET	75..270	CDD:394802	70/204 (34%)