|
Fly 2 SCSQNETAAAKVLETQRAQESGSENEETDSITDQSSQSKSIKSATQFSVQRSDTD---------- 56
|.|.|:.::| .|.::|.|| :|.||.|.|..|.| ..||:|
Mosquito 246 SSSGNDGSSA-----GRTKKSVSE-------SDSSSASSSFSSCT----SNSDSDTSSTAGDNSN 294
Fly 57 -----------------GLRMRI---SAIRPTLGVVATKKPP--KSRKMSTQDTESGCSE----- 94
|...|. :|:.....:.|.||.. |.:|.|...|.|...|
Mosquito 295 HHHQQQQDDKAKQTVGGGRHARTAASAAVASGSAIAAGKKQKILKRKKASRTATSSSSDEEDEED 359
Fly 95 -AKNRAVSKKVKVKRKKLASSSGISKSDKVSKS-------KKSQISAFSSDSEDDLPLKVHQQRA 151
...|:.||.....|....:||..|.||:..|: .||..|...|..:.:..|.:....|
Mosquito 360 LPSGRSGSKSGTANRTNEFTSSDTSSSDEDGKAFAAMRTKAKSLQSTKGSGKDGNGLLTLTDGSA 424
Fly 152 PRVL-----LSAIIQAAQ-SASKPTLDIGIS--------------SSDNELPNLVQAAIKRVESD 196
..:| ||....|.| .|..|||..|:| |||||||.||.|||:||||.
Mosquito 425 GGLLLNRPPLSTSTPAKQHGAFPPTLGGGMSSAGDGGLTAEGGSCSSDNELPALVSAAIRRVESG 489
Fly 197 TEDTTVEGSFRKAAKDKNLP--QYQSTLLQDFMEKTQMLGQT-----------VNAKLA------ 242
::..::.| .:.| ||.|:||:||:.||||||.. |:...|
Mosquito 490 SDAESIRG--------LSAPTQQYTSSLLRDFVVKTQMLGTVGGGGAGAMPAGVSGSAANSAGGG 546
Fly 243 ------------------------------------------------------EEKVAKAKEET 253
|..|.|.|.|:
Mosquito 547 GGGGGSPSSSSSSSSSSGSSSSSSSSSMEEGADPAIGSAGPGPGGGGGGGVAAFELDVRKIKTES 611
Fly 254 LVQTAVP------------------------------RKRRGR-PKKVVPTVPAP-------GNS 280
.|.:.:| .||||| ||..:...||| |:|
Mosquito 612 PVPSTLPPASVGRNTPLVNGLTTGGMKTTDLPVPAPAPKRRGRPPKSSLQAAPAPPPAARPTGSS 676
Fly 281 G----PAINESADSGVISTTST---------------------TQSTTPSPKMQNE--------- 311
. |.::||.|||::||.|: |.|:|.|.:.::|
Mosquito 677 RSVTIPTVSESPDSGILSTHSSTGSPKTDKTRSASHLRSTVGATGSSTSSRRSKSEARGSASSAS 741
Fly 312 -------------NAV---PTGSLPIASSSKPKIDMAY-----LDKRMYATERVLYPPPRSKRR- 354
|:| |.|:....|.:......:| ||:..||||||||||...|:|
Mosquito 742 SAILSAGGAAYAANSVLPAPPGAAGSGSRTSGAAASSYALTSCLDRNTYATERVLYPPRGPKKRG 806
Fly 355 ----------------------QNNKKTACSSSNKEELQLDPLWREIDVNKKFRLRSMSVGAASG 397
..|..||.|....|: :|||.|::||::|||....:| |..|.
Mosquito 807 VGRPPKKDTAAHQQPAGAGRGGPANDPTARSQQQAED-RLDPHWQKIDISKKFHEPRLS-GYKSD 869
Fly 398 TGASTTICSKVLAAKSGYVSDYGSVRHQRSSHNHNSGYKSDASCKSRYSTKSCMSRRS---RAKS 459
.|.||..|||.||::|||:||||.| ...|..:..||||||.|.:||.|.......|| ||||
Mosquito 870 GGHSTICCSKRLASQSGYISDYGGV-GASSGRSRLSGYKSDFSSRSRRSCSRAGGYRSDYGRAKS 933
Fly 460 CGYRSDCKESGKSGLRMRRKRRASMLLKS--------------------------SADD------ 492
|||||||....:..:|.:|:::.....:| |:|.
Mosquito 934 CGYRSDCSTRHRKQVRRKRRKKIGSHQQSQQQQHHNQHDHQHHNNNLSDRKNYNASSDGGGGGGS 998
Fly 493 ----TVEDQDILQLAGLSLGQSSEE---------------------------------------- 513
:|.:.:|:.:|||:||.:|:|
Mosquito 999 TKSASVGELEIMFMAGLTLGSTSDEDSSSTSSSTSSSSAESRESLFTDHSGVDRGANSSSGADKV 1063
Fly 514 ----------SNEYISKPSLKSLPTT--------------------------------------- 529
:|...:||:.| ||.|
Mosquito 1064 KRATSGRGRKANVATTKPNAK-LPRTPRKPTPPKTVAKGRGAAKAPRGRPPSSTTIDRRRKANHA 1127
Fly 530 ----------------------------------------------------SAS---------- 532
:||
Mosquito 1128 KHGSNKLDSDDEDEDEEEEAELVVKRRFGDRVRTKPLQPAPKDPPTKPSIAATASVALKQKSSAL 1192
Fly 533 -KKYGEINRYVTTGQYFGRGGS-----------------------------LSATNPDNFISKM- 566
||.|:..|.....:..||.|| |...|.|..::.|
Mosquito 1193 VKKPGQRGRPPGVKKQPGRTGSTATAAAQPAGKTLGSLDVLLAPKNSTAPVLPVNNFDRVVASMS 1257
Fly 567 -MNQRKETP-------------------------------------------------------- 574
.:..|:.|
Mosquito 1258 GSSSGKQQPGSSEAKKSSIYTFSSTTVAPKNAFAAFLLRGAAADDAAKDDAEEGGRLLGVKKLPL 1322
Fly 575 ----------------------------------------------APSKSSC------------ 581
:|:||.|
Mosquito 1323 SKANVIKNSEECSRRFQKSTSSFALGGIAGSVDLLARIADGTIPKASPTKSVCSKRSRRKSCASD 1387
Fly 582 -----------------KIKSRRSSAASMCSSYVSG----VSRMRRRHRR-KSFS---------- 614
||:.||.|..|.|||..:| .:|||||.:| :|.|
Mosquito 1388 RLEVMSVKSYGVIGSCGKIRQRRLSTMSRCSSRSAGSRHAAARMRRRKKRLRSMSVAPGTTAEMV 1452
Fly 615 -------------HNKSLNIDSKLLTEIEIITSTFNSRCRI-----QDDRLTGSSGKEKLLADAN 661
...|..:|.||..||:.::.:|:..||| .::....|||..:.::...
Mosquito 1453 SGGGGGNGGAAGGAASSSGLDLKLNVEIDRLSESFSGMCRIVGGTVNNEAGQASSGAGRSVSPPE 1517
Fly 662 KLQATLAAPSPAQQLTLNGGGPASTLSKPLKRGLKKRKLSEPLVDFAMLS------------ASA 714
:..|| .||:.|. |.|......||.:||||.||.:.|....: |:|
Mosquito 1518 EATAT-NAPAAAT--------PTSGKGHQTKRSVKKRKASEHVTDSPSTAGGANAPGGGGGGAAA 1573
Fly 715 SGTPNGSGSSNGNTKRRHKKSQSNDSSSPDDHKLPLKKRHYLLTPGER----------------- 762
.|...|:|...|..|||:||:. .:.||||||||||||||||||||:
Mosquito 1574 LGNGGGAGGGGGTGKRRNKKTV--PTQSPDDHKLPLKKRHYLLTPGEKGNNSDNNSGVDEVKTGS 1636
Fly 763 ----------PPAEVAFAN----------------GKLNAE-----------AWAAAAAAAKSTA 790
..|..|.:| |..|:. |:|:.|.::.::|
Mosquito 1637 SGGNGGGVGGSSATAAGSNVDSGNSSTSGATGSGSGSANSSFIGSHTVLNPCAFASGARSSANSA 1701
Fly 791 STKSQAQFNARSVKSALTPKKRHLLEQP----------------------TSVSGAGSS-----A 828
:|.|.. :.:...|:||||||||:.| |.|:|.|:| |
Mosquito 1702 ATGSSI---SGAATKAVTPKKRHLLKSPEPGPVPTDTELQLQIKSSDSPLTIVNGGGASGTVGDA 1763
Fly 829 SNSP-------LRIVVD--------------NNSISGGKL--------LDISPSSLCSLKQQRRG 864
.:|| .:..|| |..::|.|. ..|| ||..|.::|..|
Mosquito 1764 GSSPSDGHTVGRKAAVDGAVGGSPSNAAGQANPPVAGSKKKTNRQQEGSSIS-SSTVSRERQATG 1827
Fly 865 GA--------------------AKQKVSAAKDLVQLQSPAGSY------PPPGVFEPSVELEIQI 903
.: |:..|..:...|...:.:|:| ||||||||:|:||:.|
Mosquito 1828 ASGQPGTTSENSAGPQHRSTPPARPSVIQSSGSVHPAASSGAYSASSAGPPPGVFEPTVDLELVI 1892
Fly 904 PLSKLNESVITKAE-VESPLLSALDIKE------------------------------------- 930
|......|:|.|.| ::||.|...|:..
Mosquito 1893 PPPSSIPSLIAKVEMLDSPRLGGKDVAAAAGAIGSSSSGSSGNVATKLESEELQVLTAAQRKAAG 1957
Fly 931 -----------DTKKEVGQRVVETLLHKTGG-NLLLKRKRKKINRTGFPTVRRKKRKVSVE---Q 980
.|.....::|:|.||.|||. :||:|:||||.||||||||::||:|:... .
Mosquito 1958 LGAGSALLATISTASASSEKVLEKLLTKTGAHHLLMKKKRKKPNRTGFPTVKKKKKKLPDNDPLD 2022
Fly 981 QTTAVIDEHEPEFDPD---------------DEPLQSLRETRSSNNVNVQAAPNPPLDCERVPQA 1030
...:|:| .:||..|| ::.....|:.:...:....|| |:|||:.
Mosquito 2023 DGLSVLD-LKPEVGPDLFDSSNLTRHVPSEAEKTRMKERQQQHHPSTGKHAA------CDRVPKE 2080
Fly 1031 GEARETFVAR-TNQKAPRLSVVALERLQ----------------RPQTPARGRPR---------- 1068
||..:.|:.| |....||||||:||:|| .|.|..|||..
Mosquito 2081 GEPTDCFIERHTGVGRPRLSVVSLEKLQGKLPLPGGGSRDVATTPPATGGRGRKSVINPLAAEHQ 2145
Fly 1069 ---------------------GRKPKNREQAEAAPQPPPKS----------EPEIRPAKKRGRQP 1102
|||.|.|:: ||:|.|:: :.|||.||:|.|..
Mosquito 2146 LAAQRSRGLRDEPPAAAAGTVGRKGKKRQE---APKPLPETAVGKRQKASMDTEIRSAKERNRSK 2207
Fly 1103 KQPVLEE---------------------------PPPTPPPQQKKNKMEPNIRLPD--------- 1131
...|..| ||..||...|:...||......
Mosquito 2208 SVSVASEQLPNIVRLSETLSKGAAAKENKENSRLPPGRPPSAAKRAGKEPATSAETAPQDDAAGV 2272
Fly 1132 ---------GIDPN----------------------TNFSCKIR--------------------- 1144
.:||: :..|..:|
Mosquito 2273 IRRTRSSSVALDPSEVKKLHHHHHHDAEHESAGKGASQSSTPVRPHSGGIAALHNEDSTSLDSMP 2337
Fly 1145 -LKRRKNLE----------------AGTQPK-------KEKPVQPVTVEEIP------------- 1172
|||..:.. ..|.|| :.:...|:|..|.|
Mosquito 2338 LLKRLHSRSISRMQSVITPTVVIEPIATSPKTPGRPRGRPRTTSPITATETPNSPTATAGPGRGR 2402
Fly 1173 --------------------------PEIPVSQEEIDAEAEAKRLDS------------------ 1193
|...|:..|..|..:.:|||.
Mosquito 2403 PRTALALTGNPSAASMQRTPASPLSSPSPTVAAAERTAGRKKQRLDGRKSVPPGLAEPIESARLA 2467
Fly 1194 ------------------IPT-------------------------------------------- 1196
|||
Mosquito 2468 TRVTASKSVTPTPPVGTVIPTRLKRGKSDETLRAQQLEKPTKKPRKELPGSAEPSPETAAHLSKR 2532
Fly 1197 -----------------------------EHDPLPASESHNPGPQDY---------ASCSESSE- 1222
||||||..| ||.|: .|..|:.|
Mosquito 2533 SAIASPIVEPVDPEETAHVLQPASSTEELEHDPLPPDE----GPSDFLRLTDTPSPTSSGETREL 2593
Fly 1223 --------DKASTTSLRKLSKVKKTYLVAGLFSNHYKQSLMPPPAKVNKKPGLEEQVG----PAS 1275
.:.:.|| :||. :|.|:.|||||:.||. :...|.|.:.| |.:
Mosquito 2594 AMGGAAAGGRGAGTS-KKLP--RKKYITAGLFSDCYKD---------DGTTGGEGRSGPKTPPET 2646
Fly 1276 LLPPPPYCEKYLRRTEMDFELPYDIWWAYTNSKLPTRNVVPSWNYRKIRTNVYAESVRPNLAGFD 1340
|||||.|||::||||..||:||||:||...|.|||.||.||||||||||||||.: |:.|.:..:
Mosquito 2647 LLPPPAYCERFLRRTVRDFQLPYDLWWLQENGKLPGRNSVPSWNYRKIRTNVYYD-VKANPSTDN 2710
Fly 1341 HPTCNCKNQGEKSCLDNCLNRMVYTECSPSNCPAGEKCRNQKIQRHAVAPGVERFMTADKGWGVR 1405
:..|||| .:..|.|:||||||||||.|..||.|::|||..||||..|||:|||||.:||||:|
Mosquito 2711 NTQCNCK--PDSGCQDDCLNRMVYTECVPEQCPCGDRCRNTCIQRHEYAPGLERFMTEEKGWGIR 2773
Fly 1406 TKLPIAKGTYILEYVGEVVTEKEFKQRMASIYLNDTHHYCLHLDGGLVIDGQRMGSDCRFVNHSC 1470
::..|:|||:|:||:||||||:|||:||.::||||||||||:|||||||||.|||||||||||||
Mosquito 2774 SRERISKGTFIMEYLGEVVTEREFKERMRTMYLNDTHHYCLNLDGGLVIDGHRMGSDCRFVNHSC 2838
Fly 1471 EPNCEMQKWSVNGLSRMVLFAKRAIEEGEELTYDYNFSLFNPSEGQPCRCNTPQCRGVIGGKSQR 1535
.|||||||||||||.||.|||.|.|...|||.||||||||||||||||||.:.||||||||||||
Mosquito 2839 APNCEMQKWSVNGLFRMALFAMRDIPPNEELCYDYNFSLFNPSEGQPCRCGSEQCRGVIGGKSQR 2903
Fly 1536 VKPLPAVEAKPSGEGLSGRNGRQR---KQKAKKHAQRQAGKD-------ISSAVAV--------- 1581
:||:| :.:...|.|..|..|.|| :..|...|.:.||.| .|.|:.|
Mosquito 2904 IKPIP-LGSSGGGAGGPGGTGGQRNATEAGADTDASKAAGADGTAGGSGASGALVVELSPRSAAR 2967
Fly 1582 ------AKLQPL--------------SEKEKKLVRQFNTFLVRNFEKIRRCKAKRASDAAA---- 1622
.|.||: |.||:.|:.:.:.||:||..||||.|.:.|:.|:|
Mosquito 2968 SRKRQAKKNQPIVHLNGTPLPTFHPPSVKERALIAEHHCFLLRNLNKIRRQKERAATLASAGGGG 3032
Fly 1623 TASSPALGTTNGDIPGRRPSTPS--------SPSLAAQISALCSPRNIKTRGLTQAVHDPELEKM 1679
...:.|..|.:| |:..:..| .||||:|||||..||||:||||.....||||||.
Mosquito 3033 NGGAGAAATESG---GQGAAAGSDQTAGGSGKPSLASQISALRCPRNIRTRGLAFVEDDPELEKT 3094
Fly 1680 AKMAVVLRDICSAMETLKMSDLLTTVS-----SKKKKPIKTTLSGKLGSTAATSKVEFRSIQAQV 1739
|::||.|:|||:.:.|||....:..:: ||||.|:......| .::...|:..:
Mosquito 3095 ARIAVALKDICTEIATLKDDKGVPFITKLQLPSKKKTPLYYERIPK--------PIDLAQIETNI 3151
Fly 1740 EQGHYKTPQEFDDHMQQLFVEAKQQHGDDEGKEKALQSLKDSY----EQQ--KIASYVQLVEILG 1798
|||.|:.|:.|::.:..:...|.:.:|.:..:..|.::||..| :|| |:.:|:. .
Mosquito 3152 EQGVYRMPKVFEEDLLIMLSNAIKYYGINSPEGIASEALKSHYYTCKQQQVPKLQAYIG-----E 3211
Fly 1799 DSESLQSFKPKEVLSSEEEPGKIAVKKSP-GAKERDSPIVPLKVTPPPLLPIEASPDEDVIRCIC 1862
::|.|:.|.|| :||...||...| ..:.::.| ||:|||||
Mosquito 3212 ENELLRGFVPK------KEPADDAVPPKPKRGRRQEQP-------------------EDIIRCIC 3251
Fly 1863 GLYKDEGLMIQCSKCMVWQHTECTKADIDADNYQCERCEPREVDREIPLEEFTEEGHRYYLSLMR 1927
||:||||||||||||:||||.||||||...:||.||:|:||||:.||||.||||||::||:||||
Mosquito 3252 GLFKDEGLMIQCSKCLVWQHIECTKADPAVENYLCEKCDPREVNYEIPLNEFTEEGYQYYVSLMR 3316
Fly 1928 GDLQVRQGDAVYVLRDIPIK-DESGKVLPTKKHTYETIGAIDYQECDIFRVEHLWKNELGKRFIF 1991
|.||:||.|.||||||||:. |......|.:||||||||.|:|.||||||||.|||::.|:||::
Mosquito 3317 GKLQIRQTDTVYVLRDIPMSPDPKNPNAPVRKHTYETIGKIEYSECDIFRVESLWKDKEGRRFVY 3381
Fly 1992 GHHFLRPHETFHEPSRRFYPNEVVRVSLYEVVPIELVIGRCWVLDRTTFCKGRPMECNDEDHCYI 2056
|||:||||||:|||:||||||||:||.||||:|||||:.||||||..|||||||:: :.|.|.||
Mosquito 3382 GHHYLRPHETYHEPTRRFYPNEVMRVPLYEVIPIELVVDRCWVLDPITFCKGRPVD-SSEPHVYI 3445
Fly 2057 CELRVDKTARFFSK-AKANHPACTKSYAFRKFPEKIKISKSYAPHDVDP-----SLLKTRKQKTE 2115
|||||||:||.||| ::.:||.|.|||||.||.:|:||:|::||||:.. |:...:|:.::
Mosquito 3446 CELRVDKSARLFSKISRHSHPVCMKSYAFHKFEQKLKIAKTFAPHDLGSLAHLLSIRDKQKKGSK 3510
Fly 2116 LDVGAGPTT-----------------MHKVSGRQEQHQAKMVGRKPR-GISAPADAT-AVHVVTP 2161
.|.|:|..| .|....::.....:::...|: |:: .|.| ||...|.
Mosquito 3511 KDDGSGGQTSAGSAAGGSSGFGGAGGSHSGGSKKMTPIIQLLPPPPKTGLN--TDRTLAVQPPTG 3573
Fly 2162 VA-PNK-QMLKKRKSRLENVLITMKLKCLDAQTAQEQPIDLSYLLSGRGARQRKTQQSS 2218
.| |.: :.|.::::|||.||..:..| |.........:|:||||:|||||.|:|..|:
Mosquito 3574 GAKPTRTKTLAEKRNRLEQVLARLMQK-LTLNPNALPVVDISYLLTGRGARLRRTNNST 3631
| 
