DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14100 and MRM1

DIOPT Version :9

Sequence 1:	NP_649130.2	Gene:	CG14100 / 40132	FlyBaseID:	FBgn0036889	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_014844.3	Gene:	MRM1 / 854376	SGDID:	S000005727	Length:	412	Species:	Saccharomyces cerevisiae

Alignment Length:	201	Identity:	48/201 - (23%)
Similarity:	82/201 - (40%)	Gaps:	39/201 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 SDKGLEKNLAEQQRLGSQPFPITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKAL 279
            :::.:...|....:..::.||:.:..|.|.:|:|:|:|||:...|....:|::...|.|......
Yeast   221 NNENIPHELPYGTKTDAKKFPLGLYLDEITDPHNIGAIIRSAYFLGVDFIVMSRRNCSPLTPVVS 285

  Fly   280 RGGCGGQFRVPI-------------RDDVTWDELALTIPPEAADDCHVFIAETNQRKRENNQTID 331
            :...|....:||             ::...|..:.          .|  :|.....|....:||.
Yeast   286 KTSSGALELLPIFYVDKPLEFFTKSQEMGGWTFIT----------SH--LANATSEKYTVGKTIS 338

  Fly   332 YADIKGLGAHNL---LIIGGESHGVSEEAYR----FLNL-VGG--KGKCIYIPLAAGIDSLNVAS 386
            ..|:.|| .:.|   |::|.||.||......    |:.: .||  ||.....|:   :|||||:.
Yeast   339 MHDLNGL-CNELPVVLVVGNESQGVRTNLKMRSDFFVEIPFGGIEKGNRAPEPI---VDSLNVSV 399

  Fly   387 ALTLLL 392
            |..||:
Yeast   400 ATALLI 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14100	NP_649130.2	SpoU	131..399	CDD:223640	48/201 (24%)
		SpoU_sub_bind	141..214	CDD:285300
		SpoU_methylase	235..393	CDD:278985	46/181 (25%)
MRM1	NP_014844.3	rRNA_methyl_3	123..412	CDD:129290	48/201 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810