DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14100 and TRM3

DIOPT Version :9

Sequence 1:	NP_649130.2	Gene:	CG14100 / 40132	FlyBaseID:	FBgn0036889	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_010171.1	Gene:	TRM3 / 851446	SGDID:	S000002270	Length:	1436	Species:	Saccharomyces cerevisiae

Alignment Length:	173	Identity:	37/173 - (21%)
Similarity:	68/173 - (39%)	Gaps:	46/173 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 ITVVCDNIREPNNLGSIIRTCAALPCSQVVVTHGCCDPWESKALRGGCGGQFRVPIRDDVTWDEL 300
            :.||...:.:|.|||.|.|.|..|....:.|..                    :.:::...:..:
Yeast  1286 LIVVSSLVDKPPNLGGICRLCDVLGVGLLTVQD--------------------IKVKNHPQFKNV 1330

  Fly   301 ALT----IPPE--AADDCHVFIAETNQRKRENNQTI--DYADIKGLGAHN--------LLIIGGE 349
            |:|    :|.|  |.|:...|:.|   :|:|....|  :..| |.:...|        |:::|.|
Yeast  1331 AVTADRWMPMEEVALDEIASFMKE---KKKEGYTLIGLEQTD-KSVKLDNNFQFPKKSLILLGTE 1391

  Fly   350 SHGVSEEAYRFLNLVGGKGKCIYIPLAAGIDSLNVASALTLLL 392
            :.|:.......|:|      |:.|.....|.|:|:.:|..:::
Yeast  1392 AFGIPGTLLSELDL------CLEIQQFGVIRSMNIQTATAVIV 1428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14100	NP_649130.2	SpoU	131..399	CDD:223640	37/173 (21%)
		SpoU_sub_bind	141..214	CDD:285300
		SpoU_methylase	235..393	CDD:278985	37/173 (21%)
TRM3	NP_010171.1	SpoU-like_TRM3-like	1286..1431	CDD:349964	37/173 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0566
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810