Protein Alignment CG9330 and HEF3

DIOPT Version :10

• Sequence 1: NP_649129.1
• Gene: CG9330 / 40131
• FlyBaseID: FBgn0036888
• Length: 708
• Species: Drosophila melanogaster
• Sequence 2: NP_014384.3
• Gene: HEF3 / 855718
• SGDID: S000004959
• Length: 1044
• Species: Saccharomyces cerevisiae
• Alignment Length: 610
• Identity: 175/610 - (28%)
• Similarity: 246/610 - (40%)
• Gaps: 194/610 - (31%)

  Fly   183 FDLAFGEKVLLQNANLLLSYGRRYGLVGRNGLGKTTLLRMIAERQLQ-IPS--HISVLHVEQEVV 244
            |.||:|.|:||....|.|..||||||.|.||.||:||:|.||..|:. .|:  ....::||.::
Yeast   436 FSLAYGAKILLNKTQLRLKRGRRYGLCGPNGAGKSTLMRSIANGQVDGFPTQDECRTVYVEHDI- 499

  Fly   245 GDDTPAVESVLECDTERTRLLTREKEILAALNNGVQDATLSNELSETYASLQNIEADKAVARASV 309
             |:|.:..|||              :.:.:.|.|.:|...|.
Yeast   500 -DNTHSDMSVL--------------DFVYSGNVGTKDVITSK----------------------- 526

  Fly   310 ILKGLGFDADMQLRPTKSFSGGWRMRLALARALFSKPDLLLLDEPTNMLDIKAIIWLENYLQTWA 374
             ||..||..:|...|..|.||||:|:||||||:....|:||||||||.||...:.||.|||.|..
Yeast   527 -LKEFGFSDEMIEMPIASLSGGWKMKLALARAVLKDADILLLDEPTNHLDTVNVEWLVNYLNTCG 590

  Fly   375 TTILVVSHDRNFLDTVPTDIIHLHSQELEAYKGNYEQFEKTKTEKLKSQRREYEAQMAHRAHVQD 439
            .|.::||||..|||.|...|||....:|..||||..:|    .:|..:.:..||.
Yeast   591 ITSVIVSHDSGFLDKVCQYIIHYEGLKLRKYKGNLSEF----VQKCPTAQSYYEL---------- 641

  Fly   440 FIDRFRYNANRASSVQSKIKMLEKLPELKPVEKETVVTLKFPEVEPLNPPVLAISEVTFRYNPED 504
                      .||.::.:......|..:|..:|                .::.:|.:||:| |..
Yeast   642 ----------GASDLEFQFPTPGYLEGVKTKQK----------------AIVKVSNMTFQY-PGT 679

  Fly   505 PLPIFKGVNLSATSDSRICIVGENGAGKSTLLKIIVGQLSTIHGNIVLHRGLRIGYFAQH---HV 566
            ..|....|....:..|||.::|.||||||||:.::.|:|....|.:..|...||.|..||   |:
Yeast   680 TKPQVSDVTFQCSLSSRIAVIGPNGAGKSTLINVLTGELLPTSGEVYTHENCRIAYIKQHAFAHI 744

  Fly   567 D-HLN----------------------------------MN------------------------ 572
            : ||:                                  ||
Yeast   745 ESHLDKTPSEYIQWRFQTGEDRETMDRANRQINENDAEAMNKIFKIEGTPRRVAGIHSRRKFKNT 809

  Fly   573 --VTCVGVLAE-------------------LFPGRPDEEYRRQL-----------GSF------- 598
              ..|..:|.|                   |..|...|.:.:.:           |.|
Yeast   810 YEYECSFLLGENIGMKSERWVPMMSVDNAWLPRGELIESHSKMVAEIDMKEALASGQFRALTRKE 874

  Fly   599 --------GISGPLALQS-IASLSGGQKSRVALAKMCMAEPNFLVLDEPTNHLDIETIDALGRAI 654
                    |:...|...| |..||||||.::.||......|:.:|||||||:||.:::.||.:|:
Yeast   875 IELHCAMLGLDSELVSHSRIRGLSGGQKVKLVLAACTWQRPHLIVLDEPTNYLDRDSLGALSKAL 939

  Fly   655 NAFKGGVILVSHDERLIKVVCKELW 679
            .||:||||:::|.....|.:..|:|
Yeast   940 KAFEGGVIIITHSAEFTKNLTDEVW 964

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9330	NP_649129.1	PLN03073	1..698	CDD:215558	175/610 (29%)
HEF3	NP_014384.3	HEAT repeat	129..158	CDD:293787
		HEAT repeat	170..200	CDD:293787
		HEAT repeat	208..232	CDD:293787
		HEAT repeat	244..273	CDD:293787
		4HB	336..411	CDD:407796
		Uup	437..973	CDD:440254	174/609 (29%)
		CD_eEF3	794..861	CDD:349276	6/66 (9%)