DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9330 and CG1703

DIOPT Version :9

Sequence 1:	NP_649129.1	Gene:	CG9330 / 40131	FlyBaseID:	FBgn0036888	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_001285130.1	Gene:	CG1703 / 32112	FlyBaseID:	FBgn0030321	Length:	901	Species:	Drosophila melanogaster

Alignment Length:	762	Identity:	298/762 - (39%)
Similarity:	416/762 - (54%)	Gaps:	104/762 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PKIDHELL------TYVVGVLTGSEED-----------FESGDDIFEAVGDILQSVDCDRSEESV 60
            |::|.:.|      ..||.|...|::.           |...||..:.|.|.|.:   |..||..
  Fly   149 PELDLDDLDNEEDEVEVVAVKPASKKSKKKQQAQQKNMFAMSDDEEDEVADDLPN---DSEEEEK 210

  Fly    61 RTLC-----EQFLNIMKNNEVNVE----RKVLN---APVNIEEMA-KNMERLDKDMQSIWVANKD 112
            ..|.     |......|..|..||    .:||:   |.|:::|.. :.:.:.:.:.:|....:::
  Fly   211 EQLSNKAAKESKKEQQKQPEKEVEEQKVEQVLSEKVAAVSLKEKTPEPVPKAEPEPESEPQPDEE 275

  Fly   113 GANKVDSK-------KLGKAEAKLQQKQEKRQEVNKHGMIPVAVKLQTA-------------TAS 157
            ...:||||       |..|...|.::||:|:||..:.      ::|.|.             |.|
  Fly   276 ADAEVDSKFEESKEAKEKKLTHKEKKKQKKQQEYERQ------MELMTKKGGAGHSDLDNNFTMS 334

  Fly   158 QVTNKKNTKLDQKGLNRSMDIKIENFDLAFGEKVLLQNANLLLSYGRRYGLVGRNGLGKTTLLRM 222
            ||......|   ..|.:::|||||||.::.....|..|||||:::||||||||.||.|||||||.
  Fly   335 QVQKSAGQK---AALEQAVDIKIENFTISAKGNDLFVNANLLIAHGRRYGLVGPNGHGKTTLLRH 396

  Fly   223 IAERQLQIPSHISVLHVEQEVVGDDTPAVESVLECDTERTRLLTR----EKEILAALNNGVQDAT 283
            ||.|...||.:|.||..|||||..|..|:.::||.|..||.:|.:    ||:.:|.      |.|
  Fly   397 IATRAFAIPPNIDVLLCEQEVVATDKTAINTILEADVRRTEMLKKADELEKQFVAG------DLT 455

  Fly   284 LSNELSETYASLQNIEADKAVARASVILKGLGFDADMQLRPTKSFSGGWRMRLALARALFSKPDL 348
            :..||::|:|.|:.|.|..|.|||..||.||||..:||.|||..||||||||::|||||:.:|.|
  Fly   456 VQEELNDTFAELKAIGAYSAEARARRILAGLGFSKEMQDRPTNKFSGGWRMRVSLARALYLEPTL 520

  Fly   349 LLLDEPTNMLDIKAIIWLENYLQTWATTILVVSHDRNFLDTVPTDIIHLHSQELEAYKGNYEQFE 413
            |:||||||.||:.|:|||:||||.|..|:|:||||::|||.|..:||||..::|:.|||||..|:
  Fly   521 LMLDEPTNHLDLNAVIWLDNYLQGWKKTLLIVSHDQSFLDNVCNEIIHLDQKKLQYYKGNYSMFK 585

  Fly   414 KTKTEKLKSQRREYEAQMAH----RAHVQDFIDRFRYNANRASSVQSKIKMLEKLPELK------ 468
            |...:|.:...:|||.|...    :||.|         :.:|:..:.|..:..|..:.|
  Fly   586 KMYVQKRREMIKEYEKQEKRLRELKAHGQ---------SKKAAEKKQKESLTRKQEKNKSKQQKQ 641

  Fly   469 -----PVE-----KETVVTLKFPEVEPLNPPVLAISEVTFRYNPEDPLPIFKGVNLSATSDSRIC 523
                 |.|     ||.:|..:|||...|.||:|.:..|||.:..:.||  |..|:......||:.
  Fly   642 DEDEGPQELLARPKEYIVKFRFPEPSQLQPPILGVHNVTFAFPSQKPL--FIKVDFGIDLTSRVA 704

  Fly   524 IVGENGAGKSTLLKIIVGQLSTIHGNIVLHRGLRIGYFAQHHVDHLNMNVTCVGVLAELFPGRPD 588
            |||.||.||||.||:::|:|....|....:..|.:|.|.||..:||....:....|..|| ..|.
  Fly   705 IVGPNGVGKSTFLKLLLGELEPQEGEQRKNHRLHVGRFDQHSGEHLTAEESAAEYLQRLF-NLPH 768

  Fly   589 EEYRRQLGSFGISGPLALQSIASLSGGQKSRVALAKMCMAEPNFLVLDEPTNHLDIETIDALGRA 653
            |:.|:.|||||:........:..||||||:|||||::|::.|:.|:||||||:||||:||||..|
  Fly   769 EKARKALGSFGLVSHAHTIKMKDLSGGQKARVALAELCLSAPDVLILDEPTNNLDIESIDALAEA 833

  Fly   654 INAFKGGVILVSHDERLIKVVCKELWVCGNRTVRAIEGGLDEYKREV 700
            ||.::||||:||||||||:.....|:|..::|:..|.|..|:|::||
  Fly   834 INEYEGGVIIVSHDERLIRETGCTLYVIEDQTINEIVGEFDDYRKEV 880

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9330	NP_649129.1	PLN03073	1..698	CDD:215558	296/758 (39%)
		ABCF_EF-3	178..401	CDD:213188	124/226 (55%)
		ABC_tran_Xtn	395..480	CDD:289608	28/104 (27%)
		ABCF_EF-3	491..685	CDD:213188	87/193 (45%)
CG1703	NP_001285130.1	Uup	351..879	CDD:223562	248/545 (46%)
		ABCF_EF-3	352..573	CDD:213188	124/226 (55%)
		ABC_tran_Xtn	567..>611	CDD:289608	16/43 (37%)
		ABCF_EF-3	676..865	CDD:213188	86/191 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445834
Domainoid	1	1.000	108	1.000	Domainoid score	I313
eggNOG	1	0.900	-	-		E1_COG0488
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	356	1.000	Inparanoid score	I60
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51340
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19211
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900