DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9330 and Abcf2

DIOPT Version :9

Sequence 1:	NP_649129.1	Gene:	CG9330 / 40131	FlyBaseID:	FBgn0036888	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	XP_006235991.1	Gene:	Abcf2 / 311959	RGDID:	1304942	Length:	627	Species:	Rattus norvegicus

Alignment Length:	624	Identity:	244/624 - (39%)
Similarity:	364/624 - (58%)	Gaps:	45/624 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 DGANKVDSKKLGKAEAKLQQKQEKRQEVNKHGMIPVAVKLQTATASQVTNKKNTKLD-------- 168
            |.|.|..:||  |..||.:|:..|..|.|...:    .:.|.|.....||.:.|..|
  Rat     4 DLAKKKAAKK--KEAAKARQRPRKGHEENGDAV----TEPQVAEEKNETNGRETTGDGEVDLLTK 62

  Fly   169 -------QKGLNR-----------SMDIKIENFDLAFGEKVLLQNANLLLSYGRRYGLVGRNGLG 215
                   :|...|           |.|:.|.|..|.|..:.||.:..|.|:.||||||:|.||:|
  Rat    63 ELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIG 127

  Fly   216 KTTLLRMIAERQLQIPSHISVLHVEQEVVGDDTPAVESVLECDTERTRLLTREKEILAALNNGVQ 280
            |:.||..:.:|::.||.||.:.|:.:|:...|...::.|:|.||||. :|.||.|.||.     :
  Rat   128 KSMLLSAVGKREVPIPEHIDIYHLTREMPPSDKTPLQCVMEVDTERA-MLEREAERLAH-----E 186

  Fly   281 DATLSNELSETYASLQNIEADKAVARASVILKGLGFDADMQLRPTKSFSGGWRMRLALARALFSK 345
            ||. ..:|.|.|..|:.::||||..|||.||.||||...||.:..|.||||||||:|||||||.:
  Rat   187 DAE-CEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIR 250

  Fly   346 PDLLLLDEPTNMLDIKAIIWLENYLQTWATTILVVSHDRNFLDTVPTDIIHLHSQELEAYKGNYE 410
            |.:||||||||.||:.|.:|||..|:|:...:::|||.::||:.|.|:|||:|:::|:.|.|||:
  Rat   251 PFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYD 315

  Fly   411 QFEKTKTEKLKSQRREYEAQMAHRAHVQDFIDRFRY-NANRASSVQSKIKMLEKLPE---LKPVE 471
            |:.||:.|..::|.:.:..:....||::::|.||.: :|..|...|||.|.|:|:..   .:.|.
  Rat   316 QYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVV 380

  Fly   472 KETVVTLKFPEVEPLNPPVLAISEVTFRYNPEDPLPIFKGVNLSATSDSRICIVGENGAGKSTLL 536
            .:..::..||....:.|||:.:..|:|:|..:.|. |:..:......|:|:.:||.|||||||||
  Rat   381 SDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPC-IYNNLEFGIDLDTRVALVGPNGAGKSTLL 444

  Fly   537 KIIVGQLSTIHGNIVLHRGLRIGYFAQHHVDHLNMNVTCVGVLAELFPG-RPDEEYRRQLGSFGI 600
            |::.|:|....|.|..|..::||.:.||..:.|:::::.:..:.:.:|. :..||.|:.:|.:|:
  Rat   445 KLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGL 509

  Fly   601 SGPLALQSIASLSGGQKSRVALAKMCMAEPNFLVLDEPTNHLDIETIDALGRAINAFKGGVILVS 665
            :|...:..|.:||.|||.||.||.:....|:.|.||||||||||||||||..|||.|:||::|||
  Rat   510 TGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVS 574

  Fly   666 HDERLIKVVCKELWVCGNRTVRAIEGGLDEYKREVYKEI 704
            ||.|||:.|.:|:|||..:|:....|.:..||..:..::
  Rat   575 HDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKL 613

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9330	NP_649129.1	PLN03073	1..698	CDD:215558	243/616 (39%)
		ABCF_EF-3	178..401	CDD:213188	106/222 (48%)
		ABC_tran_Xtn	395..480	CDD:289608	27/88 (31%)
		ABCF_EF-3	491..685	CDD:213188	83/194 (43%)
Abcf2	XP_006235991.1	Uup	87..607	CDD:223562	223/527 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0000863
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.830