DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9330 and Abcf3

DIOPT Version :9

Sequence 1:	NP_649129.1	Gene:	CG9330 / 40131	FlyBaseID:	FBgn0036888	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_038880.1	Gene:	Abcf3 / 27406	MGIID:	1351656	Length:	709	Species:	Mus musculus

Alignment Length:	709	Identity:	402/709 - (56%)
Similarity:	538/709 - (75%)	Gaps:	25/709 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEYTSILQREFPKIDHELLTYVVGVLTGSEEDFESGDDIFEAVGDILQSVDCDRSEES-VRTLC 64
            |:....||:.|||:||.::..||.|||.....||||.||:.||||::||.|..|..::: :|.:|
Mouse     1 MATCADILRSEFPEIDGQVFDYVTGVLHSGSADFESVDDLVEAVGELLQEVSGDSKDDAGIRAVC 65

  Fly    65 EQFLNIMK----NNEVNVERKVLNAPVNIEEMAKNMERLDKDMQSIWVANKDGANKVDSKKLGKA 125
            ::..|.::    .|:.| .:.:|:||:   :::|.||..|.|.:...:..::.::.|::|||.||
Mouse    66 QRMYNTLRLAEPQNQGN-SQVLLDAPI---QLSKIMENYDCDTKLPGLLKREQSSTVNAKKLEKA 126

  Fly   126 EAKLQQKQEKRQEVNKHGMIPVAVK------LQTATASQVTNKKNTKLDQKGLNRSMDIKIENFD 184
            ||:|:.|||||.|..       .:|      |:.|:|||..::|.::|:..|.|:|.|::|||||
Mouse   127 EARLKAKQEKRSEKE-------TLKTSNPLVLEEASASQAGSRKESRLESSGKNKSYDVRIENFD 184

  Fly   185 LAFGEKVLLQNANLLLSYGRRYGLVGRNGLGKTTLLRMIAERQLQIPSHISVLHVEQEVVGDDTP 249
            ::||::|||..|::.|::||||||||||||||||||:|:|.|.|::|:|||:|||||||.|||||
Mouse   185 VSFGDRVLLAGADVNLAWGRRYGLVGRNGLGKTTLLKMLATRSLRVPAHISLLHVEQEVAGDDTP 249

  Fly   250 AVESVLECDTERTRLLTREKEILAALNNGVQDATLSNELSETYASLQNIEADKAVARASVILKGL 314
            |::||||.||.|..||.:|:|:...:..|..:.:.:.:|:|.|..|:.||||||.|||||||.||
Mouse   250 ALQSVLESDTVREDLLRQERELSLRIAAGRAEGSEAAQLAEIYGKLEEIEADKAPARASVILAGL 314

  Fly   315 GFDADMQLRPTKSFSGGWRMRLALARALFSKPDLLLLDEPTNMLDIKAIIWLENYLQTWATTILV 379
            ||...||.:||:.||||||||||||||||::||||||||||||||::||:|||||||||.:||||
Mouse   315 GFTPKMQQQPTREFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWPSTILV 379

  Fly   380 VSHDRNFLDTVPTDIIHLHSQELEAYKGNYEQFEKTKTEKLKSQRREYEAQMAHRAHVQDFIDRF 444
            ||||||||:.:.|||||||||.|:.|:|::|.|.|:|.|:|.:|:||||||..:|.|:|.|||||
Mouse   380 VSHDRNFLNAIATDIIHLHSQRLDGYRGDFETFIKSKQERLLNQQREYEAQQQYRQHIQVFIDRF 444

  Fly   445 RYNANRASSVQSKIKMLEKLPELKPVEKETVVTLKFPE-VEPLNPPVLAISEVTFRYNPEDPLPI 508
            ||||||||.||||:||||||||||||:||:.|.||||: .|..:||:|.:.||.|.|:|:.  .|
Mouse   445 RYNANRASQVQSKLKMLEKLPELKPVDKESEVVLKFPDGFEKFSPPILQLDEVDFYYDPKH--SI 507

  Fly   509 FKGVNLSATSDSRICIVGENGAGKSTLLKIIVGQLSTIHGNIVLHRGLRIGYFAQHHVDHLNMNV 573
            |..:::||..:||||:||||||||||:||:::|.||.:.|....||.|:||||:||||:.|::||
Mouse   508 FSRLSVSADLESRICVVGENGAGKSTMLKLLMGDLSPVRGIRHAHRNLKIGYFSQHHVEQLDLNV 572

  Fly   574 TCVGVLAELFPGRPDEEYRRQLGSFGISGPLALQSIASLSGGQKSRVALAKMCMAEPNFLVLDEP 638
            :.|.:||..|||.|:||||.|||.:||||.||::.:||||||||||||.|:|.|..|||.:||||
Mouse   573 SAVELLARKFPGLPEEEYRHQLGRYGISGELAMRPVASLSGGQKSRVAFAQMTMPCPNFYILDEP 637

  Fly   639 TNHLDIETIDALGRAINAFKGGVILVSHDERLIKVVCKELWVCGNRTVRAIEGGLDEYK 697
            |||||:|||:|||:|:|.|:|||||||||||.|::||||||||.|.:|..:|||.|:|:
Mouse   638 TNHLDMETIEALGQALNNFRGGVILVSHDERFIRLVCKELWVCENGSVTRVEGGFDQYR 696

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9330	NP_649129.1	PLN03073	1..698	CDD:215558	402/709 (57%)
		ABCF_EF-3	178..401	CDD:213188	149/222 (67%)
		ABC_tran_Xtn	395..480	CDD:289608	58/84 (69%)
		ABCF_EF-3	491..685	CDD:213188	121/193 (63%)
Abcf3	NP_038880.1	PLN03073	6..700	CDD:215558	401/704 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..171		15/48 (31%)
		ABCF_EF-3	178..401	CDD:213188	149/222 (67%)
		P-loop_NTPase	266..>363	CDD:304359	58/96 (60%)
		ABC_tran_Xtn	395..477	CDD:289608	56/81 (69%)
		ABCF_EF-3	492..683	CDD:213188	120/192 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848701
Domainoid	1	1.000	210	1.000	Domainoid score	I2830
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22784
Inparanoid	1	1.050	790	1.000	Inparanoid score	I511
Isobase	1	0.950	-	0	Normalized mean entropy	S692
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0000863
OrthoInspector	1	1.000	-	-		oto94911
orthoMCL	1	0.900	-	-		OOG6_100624
Panther	1	1.100	-	-	LDO	PTHR19211
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1720
SonicParanoid	1	1.000	-	-		X3793
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750