DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9330 and Abcf1

DIOPT Version :9

Sequence 1:	NP_649129.1	Gene:	CG9330 / 40131	FlyBaseID:	FBgn0036888	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	NP_038882.1	Gene:	Abcf1 / 224742	MGIID:	1351658	Length:	837	Species:	Mus musculus

Alignment Length:	724	Identity:	290/724 - (40%)
Similarity:	397/724 - (54%)	Gaps:	78/724 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 GDDIFEAVGDILQSVDCDRSEESVRTLCEQFLNIMKNNEVNVERKVLNAPVNI------EEMAKN 95
            |.::|||   ::|    |.|||.......:.|...|..:..:.:.|...|..:      ||.:|.
Mouse   126 GGNVFEA---LIQ----DDSEEEEEEEENRVLKPAKPEKNRINKAVAEEPPGLRSKKGKEEKSKG 183

  Fly    96 MER-----LDKDMQSIWVANKDGANKVDSKKLGKAEAKLQQKQ---EKRQEVNKHGMI----PVA 148
            ..:     .|.:.:.   ..:|.|.:.:..:.||...|.:.:|   |:::|  |.|.:    |.|
Mouse   184 KAKSKPAAADSEGEE---EEEDTAKEKEPPQQGKDRDKKEAEQGSGEEKEE--KEGDLKANDPYA 243

  Fly   149 ---------VKLQTATASQVTNKK--------------NTKLDQKGLNRSMDIKIENFDLAFGEK 190
                     :|.|.....||.:.|              .....|..|..:.|||:|.|.::...|
Mouse   244 NLSKKEKKKLKKQMDYERQVESLKAANAAENDFSVSQAEVSSRQAMLENASDIKLEKFSISAHGK 308

  Fly   191 VLLQNANLLLSYGRRYGLVGRNGLGKTTLLRMIAERQLQIPSHISVLHVEQEVVGDDTPAVESVL 255
            .|..||:|.:..||||||||.||.||||||:.||.|.|.||.:|.||..|||||.|:||||::||
Mouse   309 ELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVL 373

  Fly   256 ECDTERTRLLTREKEILAALNNGVQDATLSNELSETYASLQNIEADKAVARASVILKGLGFDADM 320
            ..||:|.|||..|:.:...|..|  |.|.:.:|.:.|..|:...|..|.|:|..||.|||||.:|
Mouse   374 RADTKRLRLLEEERRLQGQLEQG--DDTAAEKLEKVYEELRATGAAAAEAKARRILAGLGFDPEM 436

  Fly   321 QLRPTKSFSGGWRMRLALARALFSKPDLLLLDEPTNMLDIKAIIWLENYLQTWATTILVVSHDRN 385
            |.|||:.||||||||::||||||.:|.||:||||||.||:.|:|||.||||.|..|:|:||||:.
Mouse   437 QNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQG 501

  Fly   386 FLDTVPTDIIHLHSQELEAYKGNYEQFEKTKTEKLKSQRREYEAQ---------------MAHRA 435
            |||.|.||||||.:|.|..|:|||..|:|...:|.|...::||.|               .|.:
Mouse   502 FLDDVCTDIIHLDTQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEK- 565

  Fly   436 HVQDFIDRFRYNANRASSVQSKIKMLEKLPELKPVEKETVVTLKFPEVEPLNPPVLAISEVTFRY 500
            ..::.:.|.:....|.:..:..    ::.|||....||..|...||:..||:||||.:..|||.|
Mouse   566 QTKEVLTRKQQKCRRKNQDEES----QEPPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGY 626

  Fly   501 NPEDPLPIFKGVNLSATSDSRICIVGENGAGKSTLLKIIVGQLSTIHGNIVLHRGLRIGYFAQHH 565
              |...|:||.::.....||||||||.||.||||||.::.|:|:..:|.:..:..|:||:|.|.:
Mouse   627 --EGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTNGEMRKNHRLKIGFFNQQY 689

  Fly   566 VDHLNMNVTCVGVLAELFPGRPDEEYRRQLGSFGISGPLALQSIASLSGGQKSRVALAKMCMAEP 630
            .:.|:|..|....|...| ..|.::.|:.||.||:........|..||||||:||..|::...||
Mouse   690 AEQLHMEETPTEYLQRSF-NLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREP 753

  Fly   631 NFLVLDEPTNHLDIETIDALGRAINAFKGGVILVSHDERLIKVVCKELWVCGNRTVRAIEGGLDE 695
            :.|:||||||:||||:|||||.|||.:||.||:||||.|||.....:|||...:.|..|:|..|:
Mouse   754 DVLILDEPTNNLDIESIDALGEAINDYKGAVIVVSHDARLITETNCQLWVVEEQGVSQIDGDFDD 818

  Fly   696 YKREVYKEI 704
            |||||.:.:
Mouse   819 YKREVLEAL 827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9330	NP_649129.1	PLN03073	1..698	CDD:215558	286/716 (40%)
		ABCF_EF-3	178..401	CDD:213188	126/222 (57%)
		ABC_tran_Xtn	395..480	CDD:289608	25/99 (25%)
		ABCF_EF-3	491..685	CDD:213188	89/193 (46%)
Abcf1	NP_038882.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..256		30/141 (21%)
		Uup	294..825	CDD:223562	254/540 (47%)
		ABCF_EF-3	296..517	CDD:213188	126/222 (57%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	551..599		6/52 (12%)
		ABCF_EF-3	619..808	CDD:213188	88/191 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53504
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830