DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9330 and abcf3

DIOPT Version :9

Sequence 1:	NP_649129.1	Gene:	CG9330 / 40131	FlyBaseID:	FBgn0036888	Length:	708	Species:	Drosophila melanogaster
Sequence 2:	XP_017206710.1	Gene:	abcf3 / 100331227	ZFINID:	ZDB-GENE-050517-32	Length:	710	Species:	Danio rerio

Alignment Length:	706	Identity:	407/706 - (57%)
Similarity:	530/706 - (75%)	Gaps:	8/706 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSEYTSILQREFPKIDHELLTYVVGVLTGSEEDFESGDDIFEAVGDILQSVDCDRSEESVRTLCE 65
            |:.|..||:.|||:||.||..|:.|||.....|||..:::|:|:|..||.|. |::|:.:|.:|.
Zfish     2 MAAYVEILKNEFPQIDSELFEYITGVLDSGGSDFEDAEEVFDAIGGFLQEVG-DKNEDDIRNICF 65

  Fly    66 QFLNIMKNNEVN--VERKVLNAPVNIEEMAKNMERLDKDMQSIWVANKDGANKVDSKKLGKAEAK 128
            |..|.::..:.:  .::.:|.|||.:.:::.:......|:..||:..::....||:|||.|||||
Zfish    66 QMFNTLQLTKCDSGQQQVLLEAPVQLSQVSADAASSVNDVHGIWMVKRNPGTTVDAKKLEKAEAK 130

  Fly   129 LQQKQEKRQEVNKHGMIPVAVKLQTATASQVTNKKNTKLDQKGLNRSMDIKIENFDLAFGEKVLL 193
            |:.|.|:|.|.:........| |:.|:|||.::||..::|..|.|||.||:|||||::|||:.||
Zfish   131 LKAKHERRNEKDSQKSSSQLV-LEEASASQASSKKENRVDSSGKNRSYDIRIENFDVSFGERCLL 194

  Fly   194 QNANLLLSYGRRYGLVGRNGLGKTTLLRMIAERQLQIPSHISVLHVEQEVVGDDTPAVESVLECD 258
            |.|.|.|:.||||||||||||||||||:|:|.|.|::|.|||:|||||||.||:|.|::||||.|
Zfish   195 QGAELCLASGRRYGLVGRNGLGKTTLLKMLASRSLRVPLHISILHVEQEVDGDETLALQSVLESD 259

  Fly   259 TERTRLLTREKEILAALNNGVQDATLSNELSETYASLQNIEADKAVARASVILKGLGFDADMQLR 323
            |.|..||..|:.:...:.||..:...|..|||.||.|:.||||||.|||||||.||||.:.||.:
Zfish   260 TLREELLKEERRLNTHIANGTAEGLESVRLSEVYAKLEEIEADKAPARASVILAGLGFTSKMQQQ 324

  Fly   324 PTKSFSGGWRMRLALARALFSKPDLLLLDEPTNMLDIKAIIWLENYLQTWATTILVVSHDRNFLD 388
            .||.||||||||||||||||::||||||||||||||::||:|||||||||.:||||||||||||:
Zfish   325 ATKEFSGGWRMRLALARALFARPDLLLLDEPTNMLDVRAILWLENYLQTWQSTILVVSHDRNFLN 389

  Fly   389 TVPTDIIHLHSQELEAYKGNYEQFEKTKTEKLKSQRREYEAQMAHRAHVQDFIDRFRYNANRASS 453
            .|.||:||||||.||:|:|:||.|.|||.::||:|:||||||:.:|.|:|.||||||||||||:.
Zfish   390 AVVTDVIHLHSQRLESYRGDYENFIKTKEDRLKNQQREYEAQLQYREHIQVFIDRFRYNANRAAQ 454

  Fly   454 VQSKIKMLEKLPELKPVEKETVVTLKFPE-VEPLNPPVLAISEVTFRYNPEDPLPIFKGVNLSAT 517
            ||||:|:|||||||||:.||:.|.|:||: .|.|:||:|.:.||.|.|:||..|  |.|:.:||.
Zfish   455 VQSKLKLLEKLPELKPMVKESEVALRFPDNFEKLSPPILQLDEVEFGYSPEQRL--FSGLCISAD 517

  Fly   518 SDSRICIVGENGAGKSTLLKIIVGQLSTIHGNIVLHRGLRIGYFAQHHVDHLNMNVTCVGVLAEL 582
            .:||||||||||||||||||:::|:|:.:.|....||.|:||||:|||||.|::||..:.:|.:.
Zfish   518 LESRICIVGENGAGKSTLLKLLMGELTPLGGARHAHRKLKIGYFSQHHVDQLDLNVCSIELLLKR 582

  Fly   583 FPGRPDEEYRRQLGSFGISGPLALQSIASLSGGQKSRVALAKMCMAEPNFLVLDEPTNHLDIETI 647
            |||..:||||.|||.:||:|.||.:.:||||||||||||.|:|.|..|||.:|||||||||:|||
Zfish   583 FPGETEEEYRHQLGRYGITGELATRPVASLSGGQKSRVAFAQMTMPCPNFYILDEPTNHLDMETI 647

  Fly   648 DALGRAINAFKGGVILVSHDERLIKVVCKELWVCGNRTVRAIEGGLDEYKREVYKE 703
            :||.:|:|.|||||:|||||||||::||||||||....|..|:||.||| |::.:|
Zfish   648 EALAKALNKFKGGVVLVSHDERLIRMVCKELWVCEAGRVHRIDGGFDEY-RDILQE 702

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9330	NP_649129.1	PLN03073	1..698	CDD:215558	405/699 (58%)
		ABCF_EF-3	178..401	CDD:213188	153/222 (69%)
		ABC_tran_Xtn	395..480	CDD:289608	58/84 (69%)
		ABCF_EF-3	491..685	CDD:213188	120/193 (62%)
abcf3	XP_017206710.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594221
Domainoid	1	1.000	159	1.000	Domainoid score	I4071
eggNOG	1	0.900	-	-		E1_COG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H22784
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D249617at33208
OrthoFinder	1	1.000	-	-		FOG0000863
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100624
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1720
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.680