Protein Alignment Shal and kcnk3a

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001025333.1
• Gene: kcnk3a / 561866
• ZFINID: ZDB-GENE-040724-171
• Length: 390
• Species: Danio rerio
• Alignment Length: 341
• Identity: 66/341 - (19%)
• Similarity: 128/341 - (37%)
• Gaps: 112/341 - (32%)

  Fly   128 VIGDCCYEDYRDRKRENAERLMDDKLSENGDQ------NLQQLTNMRQKMWRAFENPHTSTSALV 186
            ::|...::....:.....::::||:..|..|:      |..:|..:..::     .||  .:.:.
Zfish    20 LVGAAVFDALESKMEITQKKILDDRKRELMDKYNLSKVNFDELERVVLQL-----KPH--KAGVQ 77

  Fly   187 FYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAA 251
            :.:...|:.|::    |:.|:..||      ..|..:..|:  ||:
Zfish    78 WRFAGSFYFAIT----VITTIGYGH------AAPSTDGGKV--FCM------------------- 111

  Fly   252 PDRCKFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVF--RIFKFSRHSQGLRILG 314
                                 :|..|||.         :||.:|:..  ||..|      ::.|.
Zfish   112 ---------------------FYALLGIP---------LTLVMFQSLGERINTF------VKYLL 140

  Fly   315 YTLKSCASELGFLVFSLAMA-IIIFATVMFYAEKNVNGTNFT-----SIPAAFWYTIVTMTTLGY 373
            :.||.|   ||.....::|| ::....:...:...|....|:     |...|::|..:|:||:|:
Zfish   141 HRLKKC---LGLRHTEVSMANMVCIGLISCMSTLCVGAAAFSRYEDWSFFHAYYYCFITLTTIGF 202

  Fly   374 GDMV-----------PETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRK 427
            ||.|           |:.:|...   :..|:|:.||...:.::|..|..:   |...::|.|:::
Zfish   203 GDYVALQKDNALQTNPQYVAFSF---MYILTGLTVIGAFLNLVVLRFMTM---NAEDERRDAEQR 261

  Fly   428 ARLARIRIAKASSGAA 443
            ..|:|.|    .||.|
Zfish   262 TLLSRNR----QSGGA 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	1/15 (7%)
		Ion_trans	188..415	CDD:459842	48/245 (20%)
		DUF3399	471..535	CDD:463381
kcnk3a	NP_001025333.1	Ion_trans_2	<73..132	CDD:462301	17/119 (14%)
		Ion_trans_2	173..243	CDD:462301	18/72 (25%)