Sequence 1: | NP_001097646.1 | Gene: | Shal / 40129 | FlyBaseID: | FBgn0005564 | Length: | 571 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004510.1 | Gene: | KCNQ3 / 3786 | HGNCID: | 6297 | Length: | 872 | Species: | Homo sapiens |
Alignment Length: | 380 | Identity: | 88/380 - (23%) |
---|---|---|---|
Similarity: | 154/380 - (40%) | Gaps: | 105/380 - (27%) |
- Green bases have known domain annotations that are detailed below.
Fly 142 RENAER--------LMDDKLSENGDQNLQQLTNMRQKMWRAFENP-------HTSTSALVFYYVT 191
Fly 192 G-FFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAA---- 251
Fly 252 -----PDRCKFVRSVMSIIDV---VAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQ 308
Fly 309 GLRILGYTLKSCASEL------GFLVFSLAMAIIIFATVMFYAEKNVNGTN---------FTSIP 358
Fly 359 AAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFS---RIYHQNQRAD 420
Fly 421 KRKAQRKARLARIRIAKASSGAAFVSKKKAAE---ARW---AAQESGIELDDNYR 469 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Shal | NP_001097646.1 | BTB_POZ_Shal-like | 6..144 | CDD:349727 | 1/1 (100%) |
Ion_trans | 188..415 | CDD:395416 | 61/257 (24%) | ||
DUF3399 | 445..540 | CDD:403174 | 10/31 (32%) | ||
KCNQ3 | NP_004510.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..43 | ||
Ion_trans | 139..363 | CDD:278921 | 59/248 (24%) | ||
Ion_trans_2 | 269..353 | CDD:285168 | 25/89 (28%) | ||
Selectivity filter. /evidence=ECO:0000250 | 316..321 | 3/4 (75%) | |||
Mediates interaction with calmodulin. /evidence=ECO:0000269|PubMed:27564677 | 356..537 | 13/69 (19%) | |||
KCNQ_channel | 452..656 | CDD:281513 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 575..611 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 764..872 | ||||
KCNQC3-Ank-G_bd | 780..866 | CDD:288784 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |