| Sequence 1: | NP_001097646.1 | Gene: | Shal / 40129 | FlyBaseID: | FBgn0005564 | Length: | 571 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004968.2 | Gene: | KCNC3 / 3748 | HGNCID: | 6235 | Length: | 757 | Species: | Homo sapiens |
| Alignment Length: | 636 | Identity: | 189/636 - (29%) |
|---|---|---|---|
| Similarity: | 278/636 - (43%) | Gaps: | 210/636 - (33%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 25 PLPP----------------PPMPK---DRRKT------------------DDEKLLINVSGRRF 52
Fly 53 ETWRNTLEKYPDT-LLGSNERE----FFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECL 112
Fly 113 TSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERL------------------------MDDKL 153
Fly 154 SENG------DQNLQQL------------------------TNMRQKMWRAFENPHTSTSALVFY 188
Fly 189 YVTGFFIAVSVMANVVETVPCGHR---------PGRAGTLPCGERYKIVFFCLDT---------A 235
Fly 236 CVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITD-----NDDVSGAFVTLRVF 295
Fly 296 RVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEK---------NVNG 351
Fly 352 TNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQN 416
Fly 417 QRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARWAAQESGIELDDNYRDEDIFELQHHHL 481
Fly 482 LRCLEKTTDREFVELEIPFNGQPKRPGSPS------PMASPAHSTNSAAGL 526 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Shal | NP_001097646.1 | BTB_POZ_Shal-like | 6..144 | CDD:349727 | 61/160 (38%) |
| Ion_trans | 188..415 | CDD:395416 | 99/258 (38%) | ||
| DUF3399 | 445..540 | CDD:403174 | 14/88 (16%) | ||
| KCNC3 | NP_004968.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..87 | 10/51 (20%) | |
| Important for normal N-type inactivation. /evidence=ECO:0000269|PubMed:26997484 | 1..78 | 10/42 (24%) | |||
| Potassium_chann | 1..>18 | CDD:314363 | |||
| BTB_KCNC1_3 | 89..202 | CDD:349721 | 52/113 (46%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 210..232 | 2/21 (10%) | |||
| Ion_trans | 289..550 | CDD:366146 | 100/282 (35%) | ||
| Selectivity filter. /evidence=ECO:0000250 | 503..508 | 4/4 (100%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 556..613 | 14/87 (16%) | |||
| PHA03247 | <637..752 | CDD:223021 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 682..746 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2126 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X19 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.810 | |||||