DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Shal and Kcng4

DIOPT Version :9

Sequence 1:NP_001097646.1 Gene:Shal / 40129 FlyBaseID:FBgn0005564 Length:571 Species:Drosophila melanogaster
Sequence 2:NP_001100905.1 Gene:Kcng4 / 307900 RGDID:1308553 Length:506 Species:Rattus norvegicus


Alignment Length:440 Identity:137/440 - (31%)
Similarity:235/440 - (53%) Gaps:42/440 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 EKLLINVSGRRFETWRNTLEKYPDTLLGSNE--REF--------FYDEDCKEYFFDRDPDIFRHI 95
            :::|:||.|:|:....:||:.:|.:.|....  |.:        .|||:.:|:||||:|..|..|
  Rat    58 KEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENSQEFFFDRNPSAFGVI 122

  Fly    96 LNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCC-------YEDYRDRKRENAERLMDDKL 153
            :::...|||...:..|..|:.|||:::||....:..||       .|:..:.:||.|.:....:.
  Rat   123 VSFLAAGKLVLLREMCALSFREELSYWGIEEANLERCCLRKLLKKLEEAAELRREEAAQRQQQRQ 187

  Fly   154 SENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGHRPGRAGT 218
            :.:.:....:......::....|:|.:.....||..::..|:|.:.::..|.|:|........| 
  Rat   188 ACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEDKG- 251

  Fly   219 LPCGER-YKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITDN 282
             .|..: |.|  |.::|.||..|:.|:.||...||::|:|.|..:::||::||.|||:.|.::|.
  Rat   252 -ECARKCYYI--FVVETICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDE 313

  Fly   283 DDVSG-----------AFVTLRVFRVFRI---FKFSRHSQGLRILGYTLKSCASELGFLVFSLAM 333
            ...:|           ..:.|||.|..||   .:.:|||.||:.||.|::.||.|.|.|:..|.:
  Rat   314 SPEAGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLLLFLGV 378

  Fly   334 AIIIFATVMFYAEKNVNG--TNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVL 396
            |:.:|:.:::.|| |.:|  ..||||||::|:.|::|||:|||||||.::.|::|.....|||:|
  Rat   379 AVTLFSPLVYVAE-NESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGIL 442

  Fly   397 VIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVS 446
            ::|.|...|...||..|.:.:|   .:.|.:|||.|::...::|....:|
  Rat   443 IMAFPATSIFHTFSHSYLELKR---EQEQVQARLRRLQNNNSASERELLS 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ShalNP_001097646.1 BTB_POZ_Shal-like 6..144 CDD:349727 35/119 (29%)
Ion_trans 188..415 CDD:395416 88/243 (36%)
DUF3399 445..540 CDD:403174 1/2 (50%)
Kcng4NP_001100905.1 BTB 60..167 CDD:197585 33/106 (31%)
BTB_2 60..159 CDD:280393 31/98 (32%)
Ion_trans 260..463 CDD:278921 80/205 (39%)
Ion_trans_2 397..457 CDD:285168 28/59 (47%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2126
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X19
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

Return to query results.
Submit another query.