Protein Alignment Shal and Kcnc2

DIOPT Version :9

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001346681.1
• Gene: Kcnc2 / 268345
• MGIID: 96668
• Length: 642
• Species: Mus musculus
• Alignment Length: 510
• Identity: 164/510 - (32%)
• Similarity: 254/510 - (49%)
• Gaps: 118/510 - (23%)

  Fly    40 DEKLLINVSGRRFETWRNTLEKYPDT---LLGSNEREFFYDEDC--------------------- 80
            :|::::||.|.|.||:|:||:..|.|   ||.|:|.:    .||
Mouse     7 NERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQ----GDCLTAAGDKLQPLPPPLSPPPRP 67

  Fly    81 ------------------------------------KEYFFDRDPDIFRHILNYYRTGKLHYPKH 109
                                                :|:||||.|.:|.::||||||||||.|..
Mouse    68 PPLSPVPSGCFEGGAGNCSSHGGNGGNGGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPAD 132

  Fly   110 ECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMD------------------------ 150
            .|...::|||||:||....:..||:..||..:  :||..:|
Mouse   133 VCGPLFEEELAFWGIDETDVEPCCWMTYRQHR--DAEEALDIFETPDLIGGDPGDDEDLAAKRLG 195

  Fly   151 --DKLSENG-DQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVET------ 206
              |.....| |....:...::.:||..||:|::|.:|....:.:.|||.||:....:||
Mouse   196 IEDAAGLGGPDGKSGRWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNI 260

  Fly   207 VPCGHRPGRAGTLPCGERYKI----VFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDV 267
            |.....|...||.|. .:|:|    ....::..||:.||.|:|:|:..:|::.:|::::::|||.
Mouse   261 VKNKTEPVINGTSPV-LQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDF 324

  Fly   268 VAIMPYYIGLGITD-----NDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFL 327
            |||:|:|:.:|::.     ..||.|....:|..|:.||||.:||..|||:||:||::..:|...|
Mouse   325 VAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 389

  Fly   328 VFSLAMAIIIFATVMFYAEK---------NVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAG 383
            :..||:.::||||:::|||:         ....|.|.:||..||:.:|||||||||||.|:|.:|
Mouse   390 IIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSG 454

  Fly   384 KIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKA 438
            .:||.:|:|:|||.||:||||||:||...|.......|...:||..:....:|.:
Mouse   455 MLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASS 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	48/163 (29%)
		Ion_trans	188..415	CDD:395416	99/250 (40%)
		DUF3399	445..540	CDD:403174
Kcnc2	NP_001346681.1	BTB_KCNC2_4	7..170	CDD:349722	50/168 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..98		2/52 (4%)
		Ion_trans	232..488	CDD:395416	100/256 (39%)
		Selectivity filter. /evidence=ECO:0000250	441..446		4/4 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..576

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810