Protein Alignment Shal and KCNG2

DIOPT Version :9

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_016881193.1
• Gene: KCNG2 / 26251
• HGNCID: 6249
• Length: 509
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 146/471 - (30%)
• Similarity: 232/471 - (49%)
• Gaps: 54/471 - (11%)

  Fly    27 PPPPMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYP-------------DTLLGSNEREFFYDE 78
            |.|..|.....|....::|||.|.|.......|.:.|             |.||...:.   ||.
Human    46 PWPCSPGGGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDD---YDV 107

  Fly    79 DCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRE 143
            ...|:||||.|..||.|:...|.|||...:..|..::.:|||::||....:..||....|.|:.|
Human   108 SRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEE 172

  Fly   144 NAERLMDDKLSENGDQNLQ--------QLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVM 200
            .||.....  :|.|.|...        :|...|:::....:|||:..:..:|..|:..|:||:.:
Human   173 AAEARAGP--TERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAV 235

  Fly   201 ANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSII 265
            ...:.|:|........|  .|..:.:.: |.|:|.||..|:.|:|||...|..:|.|:|:.::||
Human   236 GLCLSTMPDIRAEEERG--ECSPKCRSL-FVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNII 297

  Fly   266 DVVAIMPYYIGL--------GITDNDDVSGAFV-TLRVFRVFRIFKFSRHSQGLRILGYTLKSCA 321
            |::|::|:|:.|        |.|...:.:|..: .||..||..:.:.:|||.|||.||.|::.||
Human   298 DILALLPFYVSLLLGLAAGPGGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCA 362

  Fly   322 SELGFLVFSLAMAIIIFATVMFYAEKNVNG-TNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKI 385
            .|.|.|:..|.:|:.:||.::..||:.:.. .:|:|:||::|:.:::|||:|||||||.::.|::
Human   363 REFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQV 427

  Fly   386 VGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKA-----------S 439
            |.....|||:|::|.||..|...|||.|.:.:...:|.|..:..|.......|           |
Human   428 VALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDSTHSATATEDSSQGPDS 492

  Fly   440 SGAAFVSKKKAAEARW 455
            :|.|    ..:|:|.|
Human   493 AGLA----DDSADALW 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	39/129 (30%)
		Ion_trans	188..415	CDD:395416	85/236 (36%)
		DUF3399	445..540	CDD:403174	3/11 (27%)
KCNG2	XP_016881193.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810