Protein Alignment Shal and Kcnq5

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001128115.2
• Gene: Kcnq5 / 259273
• RGDID: 628848
• Length: 951
• Species: Rattus norvegicus
• Alignment Length: 339
• Identity: 81/339 - (23%)
• Similarity: 143/339 - (42%)
• Gaps: 65/339 - (19%)

  Fly   148 LMDDKLSENGDQNLQQLTNMRQ---KMWRAFENP-------HTSTSALVFYYVTGFFIAVSVMAN 202
            |:...||....|:.::....|:   .::...|.|       |    |.||..|.|..|     .:
  Rat    88 LLGKPLSYTSSQSCRRNVKYRRVQNYLYNVLERPRGWAFVYH----AFVFLLVFGCLI-----LS 143

  Fly   203 VVETVPCGHRPGRAGTLPCGERYKIVFFC---LDTACVMIFTAEYLLRLFAA---------PDRC 255
            |..|:|              |..|:...|   |:...:::|..|:::|:::|         ..|.
  Rat   144 VFSTIP--------------EHTKLASSCLLILEFVMIVVFGLEFIIRIWSAGCCCRYRGWQGRL 194

  Fly   256 KFVRSVMSIIDVVAIMP--YYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLK 318
            :|.|....:||.:.::.  ..:......|...:.|..:||..::.|:.:..|.....::||..:.
  Rat   195 RFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQILRMVRMDRRGGTWKLLGSVVY 259

  Fly   319 SCASEL------GFLVFSLAMAIIIFATVMFY-AEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDM 376
            :.:.||      ||||       :||::.:.| .||:.| ..|::...|.|:..:|:||:||||.
  Rat   260 AHSKELITAWYIGFLV-------LIFSSFLVYLVEKDAN-KEFSTYADALWWGTITLTTIGYGDK 316

  Fly   377 VPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSG 441
            .|.|..|:::....:|.|:...|||..::.|.|: :..|.|...|...:|:...|.:......|.
  Rat   317 TPLTWLGRLLSAGFALLGISFFALPAGILGSGFA-LKVQEQHRQKHFEKRRNPAANLIQCVWRSY 380

  Fly   442 AAFVSKKKAAEARW 455
            ||  .:|..:.|.|
  Rat   381 AA--DEKSVSIATW 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727
		Ion_trans	188..415	CDD:459842	59/247 (24%)
		DUF3399	471..535	CDD:463381
Kcnq5	NP_001128115.2	Ion_trans	125..357	CDD:459842	64/263 (24%)
		KCNQ_channel	465..653	CDD:460954