Protein Alignment Shal and Kcng1

DIOPT Version :9

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001074603.1
• Gene: Kcng1 / 241794
• MGIID: 3616086
• Length: 514
• Species: Mus musculus
• Alignment Length: 469
• Identity: 151/469 - (32%)
• Similarity: 238/469 - (50%)
• Gaps: 63/469 - (13%)

  Fly    34 DRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLG-----SNEREFF-----YDEDCKEYFFDRD 88
            |||:    :::|||.|.::.....||:::|.|.||     :|..:..     ||..|.|:||||:
Mouse    60 DRRR----QIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRN 120

  Fly    89 PDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDR--------KRENA 145
            |..|..||.:.|.|||...:..|..|:.|||.::||..|.:..||...|..:        :||..
Mouse   121 PGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREEE 185

  Fly   146 ERLMD--DKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVP 208
            |..:|  |:.||....:..:|:...:::....|.||:.....||..::..|:.|:.:...|.|:|
Mouse   186 EEPLDSEDQESEGPSASEGRLSRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLP 250

  Fly   209 CGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPY 273
            ........|  .|.:....||. :::.||..|:.|:|||...||.:..|:||.:::||:|||:||
Mouse   251 SLREEEEQG--QCSQMCHNVFI-VESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPY 312

  Fly   274 YIGLGI-----------TDNDDVSGAFVTLRVFRVFRI---FKFSRHSQGLRILGYTLKSCASEL 324
            |:.|.:           |.|..:....:.|||.|..||   .:.:|||.||:.||.|.:.|..|.
Mouse   313 YVTLLVDGAASSRRKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREF 377

  Fly   325 GFLVFSLAMAIIIFATVMFYAEKNV-NGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGG 388
            |.|:..|.:||.:||.:::..|..: :...||||||.:|:.::||||:|||||||.:..|::|..
Mouse   378 GLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVAL 442

  Fly   389 VCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEA 453
            ...|||:|::|.||..|...|||.|.:.::..:|...|:|:              ::.|.|
Mouse   443 SSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQ--------------YLIKTK---- 489

  Fly   454 RWAAQESGIELDDN 467
               :|.||:..|.:
Mouse   490 ---SQLSGMSQDSD 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	42/127 (33%)
		Ion_trans	188..415	CDD:395416	88/241 (37%)
		DUF3399	445..540	CDD:403174	6/23 (26%)
Kcng1	NP_001074603.1	BTB_POZ_KCNG1_2	60..173	CDD:349728	41/116 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..205		7/24 (29%)
		Ion_trans	227..471	CDD:395416	90/246 (37%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	424..429		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810