Protein Alignment Shal and Kcnk15

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001025463.1
• Gene: Kcnk15 / 241769
• MGIID: 2675209
• Length: 343
• Species: Mus musculus
• Alignment Length: 423
• Identity: 82/423 - (19%)
• Similarity: 136/423 - (32%)
• Gaps: 181/423 - (42%)

  Fly   111 CLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDDKLSE-------NGD--QNLQQLTN 166
            |:.||           .::|...::........:.:||:..|..|       :.|  :.|::|..
Mouse    33 CILSY-----------LLVGAAVFDALESEAERSRQRLLARKRGEFRRKYRFSADDYRELERLAL 86

  Fly   167 MRQ-----KMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPCGH-RPGR-AGTLPC--- 221
            ..:     :.||               :...|:.|::    |:.|:..|| .||. :|.:.|
Mouse    87 QAEPHRAGRQWR---------------FAGSFYFAIT----VITTIGYGHAAPGTDSGKVFCMFY 132

  Fly   222 ---------------GERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIM 271
                           |||...:..||      :.||:          ||
Mouse   133 ALLGIPLTLVTFQSLGERLNTLVRCL------LLTAK----------RC---------------- 165

  Fly   272 PYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAII 336
                 ||:. ...||                    ::.:.:.|..|  ||:       :||:..|
Mouse   166 -----LGLR-RPHVS--------------------AENMVVAGLLL--CAA-------TLALGAI 195

  Fly   337 IFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMV-----------PETIAGKIVGGVC 390
            .||        :..|..|..   |::|..:|:||:|:||.|           |..:|...   :.
Mouse   196 AFA--------HFEGWTFFH---AYYYCFITLTTIGFGDFVALQRDEALQRKPPYVAFSF---LY 246

  Fly   391 SLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKA---QRKARLARIRIAKASSGAAFVSKKKAAE 452
            .|.|:.||...:.::|..|.......:||..|:.   :|.|..:|:| |.||:...:...:...
Mouse   247 ILLGLTVIGAFLNLVVLRFLASSDAPERAVHRRVSVFRRGAPESRVR-AGASTCIPYPFHQLET- 309

  Fly   453 ARWAAQESGIELDDNYRDEDIF------ELQHH 479
              ||            ||...|      |..||
Mouse   310 --WA------------RDNPAFSPPLSPEATHH 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	4/32 (13%)
		Ion_trans	188..415	CDD:459842	51/257 (20%)
		DUF3399	471..535	CDD:463381	4/15 (27%)
Kcnk15	NP_001025463.1	Ion_trans_2	<92..151	CDD:462301	14/77 (18%)
		Ion_trans_2	195..262	CDD:462301	20/80 (25%)