Protein Alignment Shal and twk-40

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001255206.1
• Gene: twk-40 / 189006
• WormBaseID: WBGene00006691
• Length: 436
• Species: Caenorhabditis elegans
• Alignment Length: 325
• Identity: 63/325 - (19%)
• Similarity: 121/325 - (37%)
• Gaps: 78/325 - (24%)

  Fly   135 EDYRDRKRENAERLMDDKLSENGDQNLQQLT-----NMRQKMWRAFE---------NPHTSTSAL 185
            |.:...||:..|.|.:.:.|..|...::.|.     |:.:.::.||:         .|.......
 Worm    92 ERFNIHKRQMIEHLWEMRESGIGQHVVEDLAVKYVDNVTRILFEAFDTHCIGAKHLRPGGEDEDY 156

  Fly   186 VFYYVTGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFA 250
            .:.|:|..|...:::..:          |.....|...|.|::       |::.......|.|..
 Worm   157 NWTYMTALFFTTTLLTTI----------GYGNLTPVTGRGKLL-------CILYALFGVPLILIT 204

  Fly   251 APDRCKFVRSVMSIIDVVAIMPYYIGLG----------ITDNDDVSGAFVTLRVFRVFRIFKFSR 305
            ..|..||:..     ::|.:..:|..|.          |:..||                    :
 Worm   205 VADIGKFLSE-----NIVQLYTWYRKLREKCSKQKYSVISSKDD--------------------K 244

  Fly   306 HSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTT 370
            :.:|...|.: |::..|...||:.::.::.|.|..|:.   ....|.:|.|   .|:::.:||||
 Worm   245 NKEGDLNLDH-LENYISIPIFLIVAILLSYITFGAVVL---SMWEGWDFFS---GFYFSFITMTT 302

  Fly   371 LGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRI 435
            :|:||:||......|:.....:.|:.:..:.:.::...:.|..|...||.|     .||.|.:.:
 Worm   303 VGFGDIVPLKREYYILDLCYIIIGLSITTMCIDLVGIQYIRKMHYFGRAIK-----DARFALVNV 362

  Fly   436  435
             Worm   363  362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	3/8 (38%)
		Ion_trans	188..415	CDD:459842	44/236 (19%)
		DUF3399	471..535	CDD:463381
twk-40	NP_001255206.1	Ion_trans_2	<174..214	CDD:462301	10/56 (18%)
		Ion_trans_2	269..343	CDD:462301	18/79 (23%)