Protein Alignment Shal and kvs-2

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_001256236.1
• Gene: kvs-2 / 183120
• WormBaseID: WBGene00007862
• Length: 575
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 132/467 - (28%)
• Similarity: 228/467 - (48%)
• Gaps: 66/467 - (14%)

  Fly    28 PPPMPKDRRKT--------DDEKLLINVSGR----RFETWRNTLEKYPDTLLGSNEREF----FY 76
            |||:.:.|..|        .|..:.:||.|:    |.|.:.:...:..:.|..|:|...    .:
 Worm    88 PPPIGESRSTTITHDSGSNADTYMRLNVGGKSYYVRAELYTSEWTRMHELLDSSHEERLKMVDGF 152

  Fly    77 DEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCY--EDYRD 139
            |....||:.:|:..:..|:::::.||.||.|::.|:..:.|||.::.|.||.:..||.  .::..
 Worm   153 DSKTGEYYLERNAKLTDHVMDFFVTGSLHKPQNVCVERFKEELEYWKIKPDQLSTCCQIPSEHHV 217

  Fly   140 RKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVV 204
            ||........:|....:.|...  ....|..||:..|:|.:|..|.||..::.||:..||:..::
 Worm   218 RKLSRGTSFNEDDYVTDFDGAC--FAGPRLAMWKFLEDPQSSVFAAVFALLSVFFVFASVVGLIL 280

  Fly   205 ETVP-----------------------CGHRPGRAGTLPCGERYK-----------IVFFCLDTA 235
            .::|                       .|::.|....:...|..|           :....|:..
 Worm   281 GSMPEFQADSSNAATYHVMHVRSRPNDYGNKFGNDDDVAPNELLKDFVYKPTDSPNLPLTILEYI 345

  Fly   236 CVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGL-----GITDN-DDVSGAFVTLRV 294
            |:..||.|||:|....|.:.:||:..::|||:..|:|:|:.:     |:... .:.:||.:.:||
 Worm   346 CIGWFTFEYLVRFTIYPRKRQFVKKTLNIIDLSTILPFYLEICLPLFGVESRLKEFTGAMLVVRV 410

  Fly   295 FRVF---RIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTS 356
            .||.   |:||.:|:|..|:..|:||:|..:||..|...|...|:.|:|:|:|.||:...|:|.|
 Worm   411 LRVLRMARVFKLARYSTSLQTFGHTLQSSITELSMLSMFLITGIVFFSTIMYYLEKDEPHTDFYS 475

  Fly   357 IPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADK 421
            |||..|:.:|||.|:||||..|.|..||:|....|:.|::|:|.|:.:||..|:.   ..|||.:
 Worm   476 IPAGCWWCVVTMATVGYGDAKPVTTLGKLVATSTSICGIIVLAFPISMIVEKFAT---AQQRAIE 537

  Fly   422 RKAQRKARLARI 433
            .:..::|:::.:
 Worm   538 DQQIQQAQMSAV 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	35/133 (26%)
		Ion_trans	188..415	CDD:459842	82/269 (30%)
		DUF3399	471..535	CDD:463381
kvs-2	NP_001256236.1	BTB_POZ_Kv	111..199	CDD:349626	22/87 (25%)
		Ion_trans	326..535	CDD:459842	74/211 (35%)