Protein Alignment Shal and shl-1

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: NP_500975.2
• Gene: shl-1 / 177400
• WormBaseID: WBGene00022240
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 385/536 - (71%)
• Similarity: 439/536 - (81%)
• Gaps: 13/536 - (2%)

  Fly     1 MASVAAWLPFARAAAIGWVPIATHPLPPPPM---PKDRR--KTDDEKLLINVSGRRFETWRNTLE 60
            |||||||||||||||||||||:..|:|..|:   .||..  ...||||.||:||||||||:||||
 Worm     1 MASVAAWLPFARAAAIGWVPISRQPMPQAPVAIQAKDLAVDHVSDEKLAINISGRRFETWKNTLE 65

  Fly    61 KYPDTLLGSNEREFFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIM 125
            |:|:|||||||:|||||||..|||||||||||||||.:|||||||||:||||.:|||||:|||||
 Worm    66 KFPETLLGSNEKEFFYDEDTGEYFFDRDPDIFRHILTFYRTGKLHYPRHECLVAYDEELSFFGIM 130

  Fly   126 PDVIGDCCYEDYRDRKRENAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYV 190
            ||:|.|||||||:|:||||.|||.:::: ||.|.:..:| ::::|||.|||||||::.|||||||
 Worm   131 PDLISDCCYEDYKDKKRENQERLQEERV-ENADISTLKL-SLKEKMWAAFENPHTTSIALVFYYV 193

  Fly   191 TGFFIAVSVMANVVETVPCGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRC 255
            .|||||||||.|:|||:|||:....:.|  |||.|:..||.:|||||:|||.||.|||.:||||.
 Worm   194 IGFFIAVSVMCNIVETIPCGYEDNVSVT--CGEAYEEQFFVIDTACVIIFTIEYFLRLISAPDRI 256

  Fly   256 KFVRSVMSIIDVVAIMPYYIGLGITDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSC 320
            ||:||:||:|||:||||||:.|.:|||.||||.||||||||||||||||||||||||||||||||
 Worm   257 KFMRSIMSVIDVIAIMPYYVSLVLTDNKDVSGLFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSC 321

  Fly   321 ASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKI 385
            ||||||||||||||||||||:|:||||.|:.|.|||||:||||||||:||||||||||.||.|||
 Worm   322 ASELGFLVFSLAMAIIIFATIMYYAEKKVDATRFTSIPSAFWYTIVTLTTLGYGDMVPSTIMGKI 386

  Fly   386 VGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKA 450
            ||||||||||||||||||||||||||||||||||||||||:|||||||||.|.:||.|..:||:|
 Worm   387 VGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQKKARLARIRIVKNASGLALFNKKRA 451

  Fly   451 AEARWAAQESGIELDDNYRDEDIFELQHHHLLRCLEKTTDREFVELEIPFNGQPKRPGSPSPMAS 515
            .|||..|.|.|....|..|||||||:||||||:||||.|:|||||.|:.|.|....| .||..||
 Worm   452 HEARMLAFEQGHLSFDALRDEDIFEIQHHHLLQCLEKATEREFVESEVMFEGGRNTP-PPSETAS 515

  Fly   516 PAHSTNSAAGLLQSCC 531
            ....|.....|   ||
 Worm   516 LKGKTKRKRRL---CC 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	106/142 (75%)
		Ion_trans	188..415	CDD:459842	181/226 (80%)
		DUF3399	471..535	CDD:463381	33/61 (54%)
shl-1	NP_500975.2	BTB_POZ	6..149	CDD:453885	106/142 (75%)
		Ion_trans	187..416	CDD:459842	185/230 (80%)
		DUF3399	472..>511	CDD:463381	25/39 (64%)