Protein Alignment Shal and Kcnc3

DIOPT Version :9

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_036008594.1
• Gene: Kcnc3 / 16504
• MGIID: 96669
• Length: 807
• Species: Mus musculus
• Alignment Length: 637
• Identity: 188/637 - (29%)
• Similarity: 277/637 - (43%)
• Gaps: 212/637 - (33%)

  Fly    25 PLPPP-----------------PM---PKDRRKT------------------DDEKLLINVSGRR 51
            |||||                 |:   |..||..                  |..|::|||.|.|
Mouse    36 PLPPPQQQQCSQPGTAASPAGAPLSCGPGGRRAEPCPGLPAVAMGRHGGGGGDSGKIVINVGGVR 100

  Fly    52 FETWRNTLEKYPDT-LLGSNERE----FFYDEDCKEYFFDRDPDIFRHILNYYRTGKLHYPKHEC 111
            .||:|:||...|.| |.|..|.|    |.||....|:||||.|.:|.::||||||||||.|...|
Mouse   101 HETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVC 165

  Fly   112 LTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERLMDD----KLSENGDQN------------ 160
            ...::|||.|:||....:..||:..||..:  :||..:|.    ..|.|.:.|
Mouse   166 GPLFEEELGFWGIDETDVEACCWMTYRQHR--DAEEALDSFEAPDSSANANANAGGAHDAGLDDE 228

  Fly   161 --------------LQQL------------------------TNMRQKMWRAFENPHTSTSALVF 187
                          |::|                        ...:.::|..||:|::|.:|...
Mouse   229 AGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYV 293

  Fly   188 YYVTGFFIAVSVMANVVETVPCGHR---------PGRAGTLPCGERYKIVFFCLDT--------- 234
            .:.:.|||.:|:....:||    |.         ..:|..:|......|....::|
Mouse   294 AFASLFFILISITTFCLET----HEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEG 354

  Fly   235 ACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITD-----NDDVSGAFVTLRV 294
            .||:.||.|:|:|:...||:.:|::|.::|||.|||:|:|:.:|::.     ..||.|....:|.
Mouse   355 VCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRF 419

  Fly   295 FRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEK---------NVN 350
            .|:.||||.:||..|||:||:||::..:|...|:..||:.::||||:::|||:         ..|
Mouse   420 VRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSN 484

  Fly   351 GTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQ 415
            .|.|.:||..||:.:|||||||||||.|:|.:|.:||.:|:|:|||.||:||||||:||...|
Mouse   485 HTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYY-- 547

  Fly   416 NQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARWAAQESGIELDDNYRDEDIFELQHHH 480
                            .:.:||..     :.|||                            :.|
Mouse   548 ----------------SLAMAKQK-----LPKKK----------------------------NKH 563

  Fly   481 LLRCLEKTTDREFVELEIPFNGQPKRPGSPS------PMASPAHSTNSAAGL 526
            :.|                    |.:||||:      |...|.|..:.:.|:
Mouse   564 IPR--------------------PPQPGSPNYCKPDPPPPPPPHPHHGSGGI 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	59/161 (37%)
		Ion_trans	188..415	CDD:395416	99/258 (38%)
		DUF3399	445..540	CDD:403174	14/88 (16%)
Kcnc3	XP_036008594.1	BTB_KCNC1_3	91..204	CDD:349721	52/114 (46%)
		Ion_trans	290..551	CDD:395416	100/282 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810