Protein Alignment Shal and kcna2

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_031752644.1
• Gene: kcna2 / 100496794
• XenbaseID: XB-GENE-991578
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 169/491 - (34%)
• Similarity: 271/491 - (55%)
• Gaps: 66/491 - (13%)

  Fly    23 THPLPPPPMPKDRRKTDD---EKLLINVSGRRFETWRNTLEKYPDTLLGS-NEREFFYDEDCKEY 83
            |..||..|......:.|.   |:::||:||.||||...||.::|:||||. .:|..::|....||
 Frog    12 TSALPGHPQDSYDPEPDHECCERVVINISGLRFETQLKTLSQFPETLLGDPKKRMRYFDPLRNEY 76

  Fly    84 FFDRDPDIFRHILNYYRT-GKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRK---REN 144
            ||||:...|..||.||:: |:|..|.:..|..:.||:.|:     .:|:...|.:|:.:   :|.
 Frog    77 FFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEEIRFY-----ELGEEAMEIFREDEGFIKEE 136

  Fly   145 AERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVP- 208
            ...|.|::              .::::|..||.|.:|..|.:...::...|.:|:::..:||:|
 Frog   137 ERPLPDNE--------------YQKQVWLLFEYPESSGPARIIAIISVMVILISIVSFCLETLPV 187

  Fly   209 ------------CGHRPGRAGTLPCGERYK------IVFFCLDTACVMIFTAEYLLRLFAAPDRC 255
                        ..:.|....|:    ||:      ..||.::|.|::.|:.|:|:|.||.|.:.
 Frog   188 FRDENEDMHGSGVNYYPYSNSTV----RYQKSNTFTDPFFIVETLCIIWFSFEFLVRFFACPSKA 248

  Fly   256 KFVRSVMSIIDVVAIMPYYIGLGI-----TDNDDVSGAFVTL------RVFRVFRIFKFSRHSQG 309
            .|..::|:|||:|||:||:|.||.     |::.......::|      |:.|||||||.||||:|
 Frog   249 GFFTNIMNIIDIVAIIPYFITLGTELAEKTEDGQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKG 313

  Fly   310 LRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYG 374
            |:|||.|||:...|||.|:|.|.:.:|:|::.:::||.:...:.|.|||.|||:.:|:|||:|||
 Frog   314 LQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERDSQFPSIPDAFWWAVVSMTTVGYG 378

  Fly   375 DMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKAS 439
            ||||.||.|||||.:|:::|||.||||||||||||:..||:     :.:.:.:|:..::......
 Frog   379 DMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR-----ETEGEEQAQYLQVTSCPKI 438

  Fly   440 SGAAFVSKKKAAEARWAAQESGIELDDNYRDEDIFE 475
            ..:..:.|.::|.....:....|:...|:.:||..|
 Frog   439 PSSPDLQKSRSASTLSKSDYMEIQEGVNHSNEDFRE 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	44/128 (34%)
		Ion_trans	188..415	CDD:459842	107/256 (42%)
		DUF3399	471..535	CDD:463381	3/5 (60%)
kcna2	XP_031752644.1	BTB_POZ	33..159	CDD:453885	46/144 (32%)
		Ion_trans	162..420	CDD:459842	109/266 (41%)