Protein Alignment Shal and kcna1

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_004912857.1
• Gene: kcna1 / 100492822
• XenbaseID: XB-GENE-991584
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 483
• Identity: 172/483 - (35%)
• Similarity: 271/483 - (56%)
• Gaps: 59/483 - (12%)

  Fly    23 THPLPPPPMPKDRRKTDD----EKLLINVSGRRFETWRNTLEKYPDTLLGS-NEREFFYDEDCKE 82
            |..||..|........||    |:::|||:|.||||...||.::|:||||: .:|..::|....|
 Frog    12 TSVLPGHPQDSYHPDQDDHECCERVVINVAGLRFETQLKTLSQFPNTLLGNPKKRMRYFDPLRNE 76

  Fly    83 YFFDRDPDIFRHILNYYRT-GKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRK---RE 143
            |||||:...|..||.||:: |:|..|.:..|..:.||:.|:     .:|:...|.:|:.:   ||
 Frog    77 YFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFY-----ELGEEAMEKFREDEGFIRE 136

  Fly   144 NAERLMDDKLSENGDQNLQQLTNMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVP 208
            . ||.:.:|             ..::::|..||.|.:|..|.:...|:...|.:|::...:||:|
 Frog   137 E-ERPLPEK-------------EFQRQVWLLFEYPESSGPARIIAIVSVMVILISIVIFCLETLP 187

  Fly   209 -------CGHRPGRAGTLPCGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIID 266
                   ...|...:........:...||.::|.|::.|:.|.::|.||.|.:.:|.:::|:.||
 Frog   188 ELKDERIFSRRVNNSTVFYKSNIFTDPFFVVETLCIIWFSFELVVRFFACPSKPEFFKNIMNFID 252

  Fly   267 VVAIMPYYIGLGITDNDDVSG--------AFVTLRVF---RVFRIFKFSRHSQGLRILGYTLKSC 320
            :|||:||:|.|| |:..:..|        :...|||.   |||||||.||||:||:|||.|||:.
 Frog   253 IVAIIPYFITLG-TEMAEQEGPQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKAS 316

  Fly   321 ASELGFLVFSLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKI 385
            ..|||.|:|.|.:.:|:|::.:::||...:.::|.|||.|||:.:|:|||:|||||.|.||.|||
 Frog   317 MRELGLLIFFLFIGVILFSSAVYFAEAEEDESHFASIPDAFWWAVVSMTTVGYGDMYPVTIGGKI 381

  Fly   386 VGGVCSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKA 450
            ||.:|:::|||.||||||||||||:..||:     :.:.:.:|:|..:.....:|.:....:..:
 Frog   382 VGSLCAIAGVLTIALPVPVIVSNFNYFYHR-----ETEGEEQAQLLHVSTPNLASDSDLSRRSSS 441

  Fly   451 AEARWAAQESGIELD-----DNYRDEDI 473
            ..::....|  ||.|     ||:|:.:|
 Frog   442 TMSKSEYME--IEEDLNNSIDNFREANI 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	46/129 (36%)
		Ion_trans	188..415	CDD:459842	104/244 (43%)
		DUF3399	471..535	CDD:463381	1/3 (33%)
kcna1	XP_004912857.1	BTB_POZ	34..160	CDD:453885	48/144 (33%)
		Ion_trans	163..412	CDD:459842	106/254 (42%)