Protein Alignment Shal and kcnv1

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_002939028.1
• Gene: kcnv1 / 100487006
• XenbaseID: XB-GENE-956997
• Length: 503
• Species: Xenopus tropicalis
• Alignment Length: 487
• Identity: 157/487 - (32%)
• Similarity: 245/487 - (50%)
• Gaps: 71/487 - (14%)

  Fly    30 PMPKDRRKTDDEKLLINVSGRRFETWRNTLEKYPDTLLG----SNEREFFYDEDC-------KEY 83
            |.|||.       |.|||.|.||......|..:|:|.||    |..:|.:  |.|       .||
 Frog    55 PAPKDH-------LTINVGGSRFILSHKVLSNHPETRLGRLVSSGGQEVY--ELCDDANLMDNEY 110

  Fly    84 FFDRDPDIFRHILNYYRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRK--RENAE 146
            ||||...:|::|:|:|:||.||..:..|..|:.:|:.::||....|..||.|.|..:|  .|:.:
 Frog   111 FFDRSSQMFKYIMNFYKTGHLHVMEELCAVSFLQEIQYWGIDELNIDLCCRERYYRKKLMSESLD 175

  Fly   147 RLMDDKLSENGDQNLQQLT--NMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVPC 209
            ...|::..|..:::...:.  :.||.:|...|.|.:|.:|..|..::..||.:|: ||:|
 Frog   176 IKKDEEEIEAEEEDFSGVVFEHFRQTLWDILEKPGSSVAAKTFGTLSMTFIVISI-ANMV----- 234

  Fly   210 GHRPGRAGTLPCGERYKI---VFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIM 271
                     |...|...|   :...|:..|:..||.|..||......:|:|:|||::|||:|||:
 Frog   235 ---------LISSEMNSIDPPLLNALEYICITWFTLELALRFLCVKHKCRFLRSVVNIIDIVAIL 290

  Fly   272 PYYIGLGI-------TDNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLVF 329
            |:||.|.:       |:.::|.....:||:.|..|:.|..|||.||:.||.|:..|..|:|.|:.
 Frog   291 PFYITLIVENLYGESTELENVGRIVQSLRLLRSLRMLKLGRHSTGLKSLGMTIAQCYEEVGLLLL 355

  Fly   330 SLAMAIIIFATVMFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSG 394
            .|::.|.||:.:.:..|.|:..|.|||:|.|:|:...:|||:||||:.|:|..||||..:|.|||
 Frog   356 FLSVGISIFSALEYAVEHNIPDTTFTSVPNAWWWATTSMTTVGYGDIRPDTTFGKIVAFLCILSG 420

  Fly   395 VLVIALPVPVIVSNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARWAAQE 459
            :||:|||:.:|...|:..|...:..:....||:|                  .||..:...|..:
 Frog   421 ILVLALPIAIINDRFAACYFTLKIKEAALRQREA------------------LKKLMKNISAESD 467

  Fly   460 SGIELDDNYRDEDIFELQHHHLLRCLEKTTDR 491
            :.:.|.|.|. :.:.|:..   |:..|:.:.|
 Frog   468 TNVNLRDIYA-KSVMEMLR---LKSRERASTR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	45/126 (36%)
		Ion_trans	188..415	CDD:459842	88/236 (37%)
		DUF3399	471..535	CDD:463381	4/21 (19%)
kcnv1	XP_002939028.1	BTB_POZ_KCNV1	61..169	CDD:349731	40/109 (37%)
		Ion_trans	215..439	CDD:459842	89/238 (37%)