Protein Alignment Shal and kcnc1b

DIOPT Version :9

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_005174318.1
• Gene: kcnc1b / 100334453
• ZFINID: ZDB-GENE-080414-3
• Length: 598
• Species: Danio rerio
• Alignment Length: 601
• Identity: 193/601 - (32%)
• Similarity: 289/601 - (48%)
• Gaps: 118/601 - (19%)

  Fly    39 DDEKLLINVSGRRFETWRNTLEKYPDTLLG-----SNEREFFYDEDCKEYFFDRDPDIFRHILNY 98
            |.::::|||.|.:.:|:|:||...|.|.|.     .....|.||.:..|:||||.|.:|.|||||
Zfish     6 DKDRIVINVGGIKHQTYRSTLRTLPGTRLSWLAEPDAPNNFDYDANIGEFFFDRHPSVFAHILNY 70

  Fly    99 YRTGKLHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRKRENAERL-----------MDDK 152
            |||||||.|...|...|:|||||:||....:..||:..|| :.||..|.|           .||.
Zfish    71 YRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYR-QHREAEEALDSFTGGALDLGHDDP 134

  Fly   153 LSE------NGDQNLQQLTNMRQ----------------KMWRAFENPHTSTSALVFYYVTGFFI 195
            ..|      .||:.::....:.|                |.|..||:|::|..|....:.:.|||
Zfish   135 EPEGVVEAAEGDEGVEMTRRLAQGDSPDNRSGRWSRWQKKAWALFEDPYSSKYARWVAFASLFFI 199

  Fly   196 AVSVMANVVETVPCGHRP-----GRAGTLPCG-ERYKIVF---------FCLDTACVMIFTAEYL 245
            .||:....:||    |..     .|..|...| |..:.:|         ..::..||:.||.|::
Zfish   200 LVSITTFCLET----HEAFNPIINRTETYMEGNETVERIFPETETMVQLTYIEGVCVVWFTFEFI 260

  Fly   246 LRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGITD-----NDDVSGAFVTLRVFRVFRIFKFSR 305
            :|:...||:.||:|:.::|||.|||:|:|:.:|::.     ..||.|....:|..|:.||||.:|
Zfish   261 IRVTTCPDKLKFLRNTLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTR 325

  Fly   306 HSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATVMFYAE---KNVN------GTNFTSIPAAF 361
            |..|||:||:||::..:|...|:..||:.::||||:::|||   :|.|      .|:|.:||..|
Zfish   326 HFVGLRVLGHTLRASTNEFILLIIFLALGVLIFATMIYYAERIGRNPNDPDASSDTHFKNIPIGF 390

  Fly   362 WYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIVSNFSRIYH---QNQRADKRK 423
            |:.:|||||||||||.|:|.:|.:||.:|:|:|||.||:||||||:||...|.   ..|:..|:|
Zfish   391 WWAVVTMTTLGYGDMYPQTTSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKK 455

  Fly   424 ---AQRKARLARIRIAKAS---------SGAAFVSKKKAAEARW-------------AAQESGIE 463
               .:|...|......:::         |....:::::.:|.|:             .|.|....
Zfish   456 NKHIRRPPLLGSPNYCRSAVNSPRPSTHSDTCPLAQEEVSEIRYPDFKVNGEPSKAALANEDCPH 520

  Fly   464 LDDNYRDEDIFELQHHHLLRCLEKTTDRE---FVEL---EIPFNGQPKRPGSPSPMASPAHSTNS 522
            :|.....|::|            ...|||   |:..   .....|...|.|...|.:..:.|...
Zfish   521 IDQAVSPEEVF------------SPVDRERPCFLLTGGERANHTGGRVRKGYEKPWSHSSMSGGV 573

  Fly   523 AAGLLQSCCGRCCSQR 538
            |:.....|...|..|:
Zfish   574 ASVSALPCSPPCLMQQ 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	49/109 (45%)
		Ion_trans	188..415	CDD:395416	102/258 (40%)
		DUF3399	445..540	CDD:403174	20/113 (18%)
kcnc1b	XP_005174318.1	BTB	10..112	CDD:197585	47/102 (46%)
		BTB_2	10..104	CDD:280393	43/93 (46%)
		Ion_trans	230..446	CDD:278921	90/215 (42%)
		Ion_trans_2	<389..436	CDD:285168	30/46 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810