Protein Alignment Shal and kcna3

DIOPT Version :10

• Sequence 1: NP_001097646.1
• Gene: Shal / 40129
• FlyBaseID: FBgn0005564
• Length: 571
• Species: Drosophila melanogaster
• Sequence 2: XP_004910792.1
• Gene: kcna3 / 100145813
• XenbaseID: XB-GENE-1010662
• Length: 526
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 175/514 - (34%)
• Similarity: 263/514 - (51%)
• Gaps: 91/514 - (17%)

  Fly    41 EKLLINVSGRRFETWRNTLEKYPDTLLGS-NEREFFYDEDCKEYFFDRDPDIFRHILNYYRT-GK 103
            |:::||:||.||||...||.::||||||. .:|..::|....||||||:...|..||.||:: |:
 Frog    70 ERVVINISGLRFETQLKTLAQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGR 134

  Fly   104 LHYPKHECLTSYDEELAFFGIMPDVIGDCCYEDYRDRK---RENAERLMDDKLSENGDQNLQQLT 165
            :..|.:..:..:.||:.|:     .:|:...|.:|:.:   ||....|..::
 Frog   135 IRRPVNVPIDIFSEEIRFY-----ELGEEAMEKFREDEGFIREEERPLPPNE------------- 181

  Fly   166 NMRQKMWRAFENPHTSTSALVFYYVTGFFIAVSVMANVVETVP----------CGHRPGRAGTLP 220
             .::::|..||.|.:|..|.....|:...|.:|::...:||:|          ....||. ||.|
 Frog   182 -FQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDKEYSGTALPPGN-GTGP 244

  Fly   221 -CGERYKIVFFCLDTACVMIFTAEYLLRLFAAPDRCKFVRSVMSIIDVVAIMPYYIGLGI----- 279
             ....:...||.::|.|::.|:.|.|:|.||.|.:..|.:::|:|||:|||:||:|.||.
 Frog   245 YISSSFTDPFFVVETLCIIWFSFELLVRFFACPSKATFCKNIMNIIDIVAIIPYFITLGTELAER 309

  Fly   280 TDNDDVSGAFVTLRVF---RVFRIFKFSRHSQGLRILGYTLKSCASELGFLVFSLAMAIIIFATV 341
            ..|...:.:...|||.   |||||||.||||:||:|||.|||:...|||.|:|.|.:.:|:|::.
 Frog   310 QGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSA 374

  Fly   342 MFYAEKNVNGTNFTSIPAAFWYTIVTMTTLGYGDMVPETIAGKIVGGVCSLSGVLVIALPVPVIV 406
            :::||.:...:.|.|||.|||:.:|||||:|||||.|.||.|||||.:|:::|||.|||||||||
 Frog   375 VYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV 439

  Fly   407 SNFSRIYHQNQRADKRKAQRKARLARIRIAKASSGAAFVSKKKAAEARWAAQESGIELDDNYRDE 471
            |||:..||:....::                              :|::....|...|..|   |
 Frog   440 SNFNYFYHRETEGEE------------------------------QAQYLHVGSCQHLSSN---E 471

  Fly   472 DIFELQHHHLLRCLEKTTDREFVELEIPFNGQPKRPGSPSPMASPAHSTNSAAGLLQSC 530
            |:.:.:.:..|...|.....|.|              ||.|...||..|.:......:|
 Frog   472 DLKKARSNSSLSKSEYMVIEEGV--------------SPGPFKQPAFKTGNCTTNNPNC 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shal	NP_001097646.1	BTB_POZ_Shal-like	6..144	CDD:349727	39/107 (36%)
		Ion_trans	188..415	CDD:459842	110/245 (45%)
		DUF3399	471..535	CDD:463381	13/60 (22%)
kcna3	XP_004910792.1	BTB_POZ	70..196	CDD:453885	45/144 (31%)
		Ion_trans	199..449	CDD:459842	112/250 (45%)