Protein Alignment Dred and BIK1

DIOPT Version :10

• Sequence 1: NP_649124.1
• Gene: Dred / 40124
• FlyBaseID: FBgn0036882
• Length: 1339
• Species: Drosophila melanogaster
• Sequence 2: NP_009901.1
• Gene: BIK1 / 850328
• SGDID: S000000534
• Length: 440
• Species: Saccharomyces cerevisiae
• Alignment Length: 560
• Identity: 120/560 - (21%)
• Similarity: 212/560 - (37%)
• Gaps: 174/560 - (31%)

  Fly     2 MSPRELKLGQRVEVTGKNL-QGKVAYVGRTNFAAGLWYGVVLDEPLGKNNGSVHGSIYFKCP-TN 64
            |...:.|:|..:::  .|| :|::.|||..:..||::.||.|...:|||:||..|..||:.. ..
Yeast     1 MDRYQRKIGCFIQI--PNLGRGQLKYVGPVDTKAGMFAGVDLLANIGKNDGSFMGKKYFQTEYPQ 63

  Fly    65 CGLFVRAQQLVRIAELPKGGDNRKADEMQRDGARAKLSRRSGSGKSVEEQDNQREQQASTSGKVK 129
            .|||::.|::..:.|                                         :||.|...:
Yeast    64 SGLFIQLQKVASLIE-----------------------------------------KASISQTSR 87

  Fly   130 ATSSTPSPQHKNRNTHSSMETSLAKTSGKFLATHQQPLQLPKNPVTCESSVRNSQSKETGEVTLS 194
            .|:..|....|||        |:.:.:.:|     .|:..||:|....|.  ...|:.:|.
Yeast    88 RTTMEPLSIPKNR--------SIVRLTNQF-----SPMDDPKSPTPMRSF--RITSRHSGN---- 133

  Fly   195 PKKSSDIEQSKKHSQQETNETNQPASKEVEPKNENELQSTEAANSMLDTP-------VNPLQTST 252
             ::|.|.|.|..|.|||....|:....||    ::.|.|...||....:.       :|.|.:|
Yeast   134 -QQSMDQEASDHHQQQEFGYDNREDRMEV----DSILSSDRKANHNTTSDWKPDNGHMNDLNSS- 192

  Fly   253 IGQLPPQKASAQLTPPPLTCNQRRSTSYTQLRPTR---ISQPKPTTAQAQSSTAQLTLAMPVPLA 314
              ::..:...||||...|   ||:...|.:|...:   :.:.:||..:.:              |
Yeast   193 --EVTIELREAQLTIEKL---QRKQLHYKRLLDDQRMVLEEVQPTFDRYE--------------A 238

  Fly   315 LAPKRSKTSMSPTSSIKRVAPAAFVEPRFLEILRPQFTPGPALRTPSSVAPPLDNPELRQLREEL 379
            ...:|.|                                                 |:..|:::|
Yeast   239 TIQEREK-------------------------------------------------EIDHLKQQL 254

  Fly   380 QLLRGQKSEDKLKLLELERMRIHNEQLMEFKSQIMAQQVLLQRELQRSRHELREAQDVSSKLKRE 444
            :|.|.|:::.| :..:.|     ||||:...|| :.:::....|...|.::...|.:....||::
Yeast   255 ELERRQQAKQK-QFFDAE-----NEQLLAVVSQ-LHEEIKENEERNLSHNQPTGANEDVELLKKQ 312

  Fly   445 LDEIAESIELLTLDK-EMAEERMETLQMELEMAQERNDELSLDVEILKAEQEEQQGQRIEKSEKQ 508
            |:::....:...|.| :.|:|| |.|:|       .||.||.:.:.|..|....:.|  :.|.::
Yeast   313 LEQLRNIEDQFELHKTKWAKER-EQLKM-------HNDSLSKEYQNLSKELFLTKPQ--DSSSEE 367

  Fly   509 IGSGVTNQSAGEFLRLEQYNQRLRETVVRLRDTLAEEKQI 548
            :.| :|.       :||:.|:::::.......|..|...|
Yeast   368 VAS-LTK-------KLEEANEKIKQLEQAQAQTAVESLPI 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dred	NP_649124.1	CAP_GLY	9..74	CDD:460154	24/66 (36%)
		Metaviral_G	171..306	CDD:462833	34/144 (24%)
		Smc	<373..>704	CDD:440809	43/177 (24%)
		Dynactin	688..967	CDD:463591
		Smc	<1092..>1305	CDD:440809
BIK1	NP_009901.1	CAP_GLY	8..73	CDD:460154	24/66 (36%)
		SMC_prok_B	193..>395	CDD:274008	56/292 (19%)