Protein Alignment Dred and clip-1

DIOPT Version :10

• Sequence 1: NP_649124.1
• Gene: Dred / 40124
• FlyBaseID: FBgn0036882
• Length: 1339
• Species: Drosophila melanogaster
• Sequence 2: NP_001022682.1
• Gene: clip-1 / 176307
• WormBaseID: WBGene00010796
• Length: 937
• Species: Caenorhabditis elegans
• Alignment Length: 1025
• Identity: 195/1025 - (19%)
• Similarity: 359/1025 - (35%)
• Gaps: 344/1025 - (33%)

  Fly     3 SPREL----KLGQRVEV--TGKNLQGKVAYVGRTNFAAGLWYGVVLDEPLGKNNGSVHGSIYFKC 61
            :|:|:    .:|:.|:|  .||   |.:.|||..:...|::.|:.|.||.||::|:..|..||..
 Worm    11 NPQEVVTAHDIGRLVDVVNVGK---GFLRYVGPIHGKDGMFCGIELLEPNGKHDGTFQGVSYFIA 72

  Fly    62 PTNCGLFVRAQQLVRIA----ELPK----GGDNR------------------------------- 87
            ....|:|.   .:.|:.    ||||    ...||
 Worm    73 TPYHGIFA---PIFRVTLDAEELPKPPPPNPSNRLSRSALPALQLRNPLTQERKPEEDVMSTSVY 134

  Fly    88 ------------------KADEMQ-------RDG-----------------ARAKLSRRSG---- 106
                              :.|.||       .||                 :....:.|.|
 Worm   135 VSSSTKPIAIPTKQCRPPETDPMQMSMFSDMMDGSMFSNGSWSDIADSMITSNCTFTVRKGLPID 199

  Fly   107 ------------SGKSVEEQDNQREQQASTS---GKVK--------------------ATSSTPS 136
                        |..:::.:..:||:|..:|   |:.:                    .|.:.|.
 Worm   200 DDGDLMSVPMVQSVFNIDREALRREEQLQSSIVLGESRIGVEHLPIIEDENELETPLVETRTMPL 264

  Fly   137 PQHKNRNTHSSMETSLAKTSGKFLATHQQPLQLPKNPVTCESSVRNS-----QSKETG------E 190
            |...|.|..:...|:          |..:| :.||..:....::.||     |...:|      |
 Worm   265 PNDLNANFSNKNSTT----------TFVEP-ETPKVEIRENGNLDNSIETPPQQSPSGSSMVSHE 318

  Fly   191 VTLSPKK---SSDIEQSKKHSQQE----TNETNQPASKEVEPK--------NENELQSTEAANSM 240
            ...|.||   .||...:||..:.|    ..:..:||:....||        ::::|...:...|:
 Worm   319 SDSSSKKDDTKSDKSPTKKSQKMEEKPVVKKKEEPAAPPPPPKFPVKQKAPSKHQLMMEQLKASI 383

  Fly   241 LDTPVNPLQ--TSTIGQLPP---------QKASAQLTPPPLTCNQRRSTSYTQLRPTRI---SQP 291
            ......|.:  .|.:..|||         .|...::|..|     ||:.:.|.|:....   :.|
 Worm   384 EAEKTKPKKEIKSRVSLLPPPAPKAPQKENKEGGEMTETP-----RRTITKTPLKTVNAKAKTSP 443

  Fly   292 KPTTAQAQSSTAQLTLAMPV-----------------PLALAPKRSKTSMSPTSSIKRVAP---A 336
            .|...:.:.....|.:|.|.                 |...|.|:...|..|::|.....|   :
 Worm   444 TPPVERQKKERKPLYVAPPAKERVEKEKKIPSKPVVSPPTTAEKKPVVSSIPSTSSASKGPFPTS 508

  Fly   337 AFVEPRFLEILRPQFTPGPALRTPSSVA--------PPLDNPELRQLREELQLLRGQKSEDKLKL 393
            :|...:.         .||...:.||..        ||:|.      :|:|..|:......:..|
 Worm   509 SFAGGKL---------QGPRKTSSSSTTTSAKKQKNPPIDE------KEKLSRLQHSTHAFEATL 558

  Fly   394 LELERMRIHNEQLMEFKSQIMAQQVLLQRELQRSRHELRE--AQDVSSKLKRELDEI----AESI 452
            :.:.|:...||:.:...|:...::|....:|::...|.|:  .:|| .::|....::    |.::
 Worm   559 IVMNRINEDNERKLGNISEQYEKKVSELGDLKKMLDEARKKFEEDV-EQMKNSNQQVIRNHANAV 622

  Fly   453 ELL--TLDKEMAEERMETLQMELEMAQER----------NDELSLDVEIL--KAEQEEQQGQRIE 503
            |.|  |.:.::||:..|   .|....:||          |:.....|..|  |..:.|:|.:::.
 Worm   623 ESLQKTHETQIAEKNKE---FERNFEEERARREAEVCAMNNRHQKVVACLDEKISEAEKQCEQLN 684

  Fly   504 KSEKQIGSGVTNQSAGEFLRLEQYNQRLRETVVRLRDTLAEEKQIGQRTHKELETKHSEINELKS 568
            ..:|.:.:.:.|.       .:..||.|.:.:..|:..              ||.|.:|:.||:.
 Worm   685 VDKKVLQAALAND-------CDHRNQMLTKEISSLQTA--------------LEMKSAEMKELRQ 728

  Fly   569 IKELLSRRVDNMEMQLMDL----------KEQVDASLGAEAMVTQLASLKLELED-RVKLLEDEV 622
            ..:.||.:||.:.::.:::          |:.:|..:..|.::.|      ::|| |.|.:.||
 Worm   729 KNQNLSLQVDEIPLKELEISKWKHKSNEYKQMLDQKINGEKILVQ------QIEDLRRKQIHDE- 786

  Fly   623 NELEALEQIQEQLIESNQELETDLREEIDKLSGHVKILEQQKNAAMESLYDRDVTIMKFRDLVRQ 687
            .|.||::: ...|::...|            :|....:....:|.|||.:... |.::||.
 Worm   787 EEKEAMKR-SFDLMQFKYE------------NGDDPNVTSVMSAPMESRFSTP-TKVQFRS---- 833

  Fly   688 LQEQLQLRADGTLSIEDFSSANESQQEDGSNQSQTDYQHIFSVSKAYGRALEQQIKTVELRLQRQ 752
                 :..|.|:..| ..:::|...|...::....|..:..::|          :.|..:||...
 Worm   834 -----RSSASGSRPI-SMATSNGGDQRLSTSSHHDDSMNRSTIS----------MYTSHIRLPEN 882

  Fly   753 HLEHVLAFVPEQFL-LRGGEHDVVLVMLLLERMNEKLTIVCQAINEKFPT 801
            |.:.|: :.|::.: .|.|.            ::::|.|..:  |:..||
 Worm   883 HADDVI-YAPDEIISSRSGS------------ISQRLAISIE--NDGEPT 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dred	NP_649124.1	CAP_GLY	9..74	CDD:460154	22/66 (33%)
		Metaviral_G	171..306	CDD:462833	34/174 (20%)
		Smc	<373..>704	CDD:440809	73/361 (20%)
		Dynactin	688..967	CDD:463591	20/115 (17%)
		Smc	<1092..>1305	CDD:440809
clip-1	NP_001022682.1	CAP_GLY	21..85	CDD:460154	22/69 (32%)
		PTZ00121	<364..793	CDD:173412	94/480 (20%)