DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cpr76Bd and attf-6

DIOPT Version :9

Sequence 1:	NP_001262052.1	Gene:	Cpr76Bd / 40123	FlyBaseID:	FBgn0036881	Length:	1231	Species:	Drosophila melanogaster
Sequence 2:	NP_871800.1	Gene:	attf-6 / 173148	WormBaseID:	WBGene00012474	Length:	1634	Species:	Caenorhabditis elegans

Alignment Length:	924	Identity:	181/924 - (19%)
Similarity:	289/924 - (31%)	Gaps:	304/924 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 VGSSGAAYQSTAGIEGLSHGGITQINKYIAPVQKSLFSPSAEYGGAGITYADKSPAAKYATVVPS 141
            :|:.|||..|..|.....||   :..|.:..:|..:....:....|....|:.| |.:.....|:
Worm   382 LGAQGAAGASEPGSSSSIHG---KKGKTVRELQTEMMKGESVKEKAARMRAEAS-AGRSQAPGPA 442

  Fly   142 GIEIKNLVSPAVTKLDNSYLPPSPGITKVATYTSPGYSYSSASPG--------------ISKVAT 192
                   .:||.::|.:   ||.            .:..|.:.||              |..:.|
Worm   443 -------PAPAASELQD---PPQ------------DFGLSMSDPGSDSETEEHQKQEKHIPAMVT 485

  Fly   193 YSSPSLSSVPYYAPPVTSKVETYSS---PAYTYSKTTPGY--SKVETYSSPGYSYGQISPGISRI 252
            ..|..||::     |||.|..:.||   |..:.|.:|||.  .:..|.|:.     .:.|..:.:
Worm   486 RRSARLSAL-----PVTPKKASSSSKMPPPPSPSPSTPGRRGRRPRTLSTM-----SMEPAAAAV 540

  Fly   253 ATYSPSVSYSAPTIAKVSTYS-----APSV---------KLATTSSLLSSHGTGYSASYA----- 298
             |.:|.....:.:.||||..:     |||.         :..:|.|:........|::.|
Worm   541 -TPAPRGRPRSRSAAKVSENTEPLSEAPSAPVKRGRGRPRSRSTMSITEDSEPSTSSTAAKRSKR 604

  Fly   299 -----------------------PSITKYSQVSDVSHQYI--------------SKPI------- 319
                                   ||.|....|.||..:.:              ..|:
Worm   605 AESDEEEEQDLKLTNKSPEKPKKPSKTTEETVGDVLKKRLRDTAKTTATVIHTPGPPLRTRKMER 669

  Fly   320 VAAYPAIT---KVAASYGGTASGALS-HQYVSQPAIAKVSTYAAPTVATYSSGPAIS----KLST 376
            :.|..|:|   |......|:|..::: .::..:..|.:..|...|. .|....|.||    .|..
Worm   670 MRAPTAVTSSKKEKPKNAGSADSSINEEEHEDETMILEEQTLDLPQ-QTSQQEPRISCGSELLDE 733

  Fly   377 SYGAS--GSGAVSHQYVSKPAVAIAAPAVAKVATYAAPAISSYSTGPAISKVASYAAPTVSTYSS 439
            .:.||  .||.|.           :||.:.|......|..|..|..|....:...|.|.::.
Worm   734 QFDASEEHSGTVP-----------SAPELTKNPAPPVPEASEASAEPPKIDIPEQATPILAL--- 784

  Fly   440 GYGYGSSGSGAVSHQYVSKPAVAISAA--------PAIAKVATYAAPAISTYAAAPVVTKVATGY 496
                      |::...||..|:....|        |..::::..|..|:.|.:..|..:
Worm   785 ----------ALALPTVSPTALEPPKAQENPTAELPTTSEISGRAPQALPTSSQTPPTS------ 833

  Fly   497 GGSGSGYSSGAVSHQYVSKPAVAKVATYAAPAI-----STYSAAPAVTKIATSYGGSGHGAVSHQ 556
             ||.:......:| :.:|.....|....|.||:     ||...||..:
Worm   834 -GSAAPPVDDLLS-EILSGAKTTKTRKAAPPAVQKSISSTTQQAPPTS----------------- 879

  Fly   557 YVSKPAVAISAAPAI----AKVATYASPAISTYAT--APVVSKVATYAAPSIATYSSAPA----- 610
             |..|..:.||||.:    :::.:.|....:|..|  .||..|..:..||.|:  .|||.
Worm   880 -VQAPPTSCSAAPPVDDLLSEILSGAKTTKTTKTTKMPPVDQKKISSEAPPIS--DSAPTSVHQQ 941

  Fly   611 -------LAKVSYS----------------------------------QAADVSHQYISKP--IV 632
                   :....|.                                  ||::.|.....||  :|
Worm   942 TPKSPKQILNSKYGLDISDSEDEEEEEEERGMEIVEEEEEAPPISDSLQASEPSSTATVKPEKVV 1006

  Fly   633 AAYPAAAPAVATYS-----------SAPAITKLSTSYESSGSGAVSHQYVSKPAVAK-----VAA 681
            |.....:|.:.:.|           .|||.||:...        ::.|..|:|...|     :|.
Worm  1007 AVVKIFSPEIDSTSVEAPPEASVPPKAPAATKIDNQ--------LADQQASEPEPPKARKLPIAR 1063

  Fly   682 YAAPAISTYATAPAVSTYSSAPVVAKVATGYGGSGSGYSSGAVSHQYISKPAVAIASAPAIAKVA 746
            ...|.|.....||:.||.|...:::.:..|         :..........|...:|.......:|
Worm  1064 KIPPKIKISLPAPSSSTTSDDDLMSDILAG---------AKTTKTTKPKAPPTRVAQTTRTKNLA 1119

  Fly   747 --TYAAPAISAYSSAPSLTKIATGYGESAHGGALSHQYISKPAIAVAPVAPVLSKTYLPAAPAVA 809
              ..|:|...|.::||                  ..|||.|...:|.|.:. .|.|..|:||..|
Worm  1120 QKRKASPPTPAGTTAP------------------KRQYIKKSIDSVLPPSS-SSSTEPPSAPDSA 1165

  Fly   810 KVATGYGISGSGAV 823
            ...:... .|.||:
Worm  1166 STTSSMK-KGGGAI 1178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cpr76Bd	NP_001262052.1	Chitin_bind_4	1156..1208	CDD:278791
attf-6	NP_871800.1	235kDa-fam	<20..>223	CDD:130673
attf-6	NP_871800.1	PHA03247	<735..1080	CDD:223021	78/404 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28JAF
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900